Louis Martens Kunkel

Louis Martens Kunkel, Ph.D.

Professor of Genetics and Pediatrics, Harvard Medical School

Director, Genomics Program

617-355-7576

Kunkel Lab Website

Publications

Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia.

Authors: Authors: Ziv S, Brenner O, Amariglio N, Smorodinsky NI, Galron R, Carrion DV, Zhang W, Sharma GG, Pandita RK, Agarwal M, Elkon R, Katzin N, Bar-Am I, Pandita TK, Kucherlapati R, Rechavi G, Shiloh Y, Barzilai A.
Hum Mol Genet 2005-10-01
View full abstract on Pubmed

Comparative analysis of algorithms for identifying amplifications and deletions in array CGH data.

Authors: Authors: Lai WR, Johnson MD, Kucherlapati R, Park PJ.
Bioinformatics 2005-10-01
View full abstract on Pubmed

Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice.

Authors: Authors: Yang K, Fan KH, Lamprecht SA, Edelmann W, Kopelovich L, Kucherlapati R, Lipkin M.
Int J Cancer 2005-09-10
View full abstract on Pubmed

(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition.

Authors: Authors: Owen BA, Yang Z, Lai M, Gajec M, Gajek M, Badger JD, Hayes JJ, Edelmann W, Kucherlapati R, Wilson TM, McMurray CT.
Nat Struct Mol Biol 2005-08-01
View full abstract on Pubmed

Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice.

Authors: Authors: Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, Russell R, Carrión DV, Chin L, Kucherlapati R, Kolodner RD, Edelmann W.
Nat Genet 2005-07-01
View full abstract on Pubmed

Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system.

Authors: Authors: Dziejman M, Serruto D, Tam VC, Sturtevant D, Diraphat P, Faruque SM, Rahman MH, Heidelberg JF, Decker J, Li L, Montgomery KT, Grills G, Kucherlapati R, Mekalanos JJ.
Proc Natl Acad Sci U S A 2005-03-01
View full abstract on Pubmed

The PTPN11 gene is not implicated in nonsyndromic hypertrophic cardiomyopathy.

Authors: Authors: Roberts AE, Hult B, Rehm HL, Rehm HL, McDonough B, Barr S, Seidman CE, Seidman JG, Kucherlapati RS.
Am J Med Genet A 2005-01-30
View full abstract on Pubmed

Mlh1 mediates tissue-specific regulation of mitotic recombination.

Authors: Authors: Shao C, Deng L, Chen Y, Kucherlapati R, Stambrook PJ, Tischfield JA.
Oncogene 2004-12-02
View full abstract on Pubmed

Association of the DTNBP1 locus with schizophrenia in a U.S. population.

Authors: Authors: Funke B, Finn CT, Plocik AM, Lake S, DeRosse P, Kane JM, Kucherlapati R, Malhotra AK.
Am J Hum Genet 2004-11-01
View full abstract on Pubmed

Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility.

Authors: Authors: Yang G, Scherer SJ, Shell SS, Yang K, Kim M, Lipkin M, Kucherlapati R, Kolodner RD, Edelmann W.
Cancer Cell 2004-08-01
View full abstract on Pubmed