Luke H Chao

Luke H Chao, Ph.D.

Assistant Professor of Genetics

617-724-2323

Chao Lab Website

Publications

A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme.

Authors: Authors: Chao LH, Stratton MM, Lee IH, Rosenberg OS, Levitz J, Mandell DJ, Kortemme T, Groves JT, Schulman H, Kuriyan J.
Cell 2011-09-02
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Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.

Authors: Authors: Chao LH, Pellicena P, Deindl S, Barclay LA, Schulman H, Kuriyan J.
Nat Struct Mol Biol 2010-03-01
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Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.

Authors: Authors: Young MA, Shah NP, Chao LH, Seeliger M, Milanov ZV, Biggs WH, Treiber DK, Patel HK, Zarrinkar PP, Lockhart DJ, Sawyers CL, Kuriyan J.
Cancer Res 2006-01-15
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Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site.

Authors: Authors: Nunn CM, Jeeves M, Cliff MJ, Urquhart GT, George RR, Chao LH, Tscuchia Y, Djordjevic S.
J Mol Biol 2005-07-01
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Front Mol Biosci

Authors: Authors: Absence of Cardiolipin From the Outer Leaflet of a Mitochondrial Inner Membrane Mimic Restricts Opa1-Mediated Fusion
2021; 769135(8).