Marc Vidal

Marc Vidal, Ph.D.

Professor of Genetics

617-632-5180

Marc Vidal Website

Publications

Survey of variation in human transcription factors reveals prevalent DNA binding changes.

Authors: Authors: Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML.
Science 2016-03-25
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A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States.

Authors: Authors: Chiu CN, Rihel J, Lee DA, Singh C, Mosser EA, Chen S, Sapin V, Pham U, Engle J, Niles BJ, Montz CJ, Chakravarthy S, Zimmerman S, Salehi-Ashtiani K, Vidal M, Schier AF, Prober DA.
Neuron 2016-02-17
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Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

Authors: Authors: Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M.
Cell 2016-02-11
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Network-based in silico drug efficacy screening.

Authors: Authors: Guney E, Menche J, Vidal M, Barábasi AL.
Nat Commun 2016-02-01
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MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy.

Authors: Authors: Neupane M, Clark AP, Landini S, Birkbak NJ, Eklund AC, Lim E, Culhane AC, Barry WT, Schumacher SE, Beroukhim R, Szallasi Z, Vidal M, Hill DE, Silver DP.
Cancer Discov 2016-01-01
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Global Edgetic Rewiring in Cancer Networks.

Authors: Authors: Wang Y, Sahni N, Vidal M.
Cell Syst 2015-10-28
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A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.

Authors: Authors: Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA, Tantisira KG, Qiu W, Raby BA, Silverman EK, Vidal M, Weiss ST, Barabási AL.
Hum Mol Genet 2015-06-01
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Human gene-centered transcription factor networks for enhancers and disease variants.

Authors: Authors: Fuxman Bass JI, Sahni N, Shrestha S, Garcia-Gonzalez A, Mori A, Bhat N, Yi S, Hill DE, Vidal M, Walhout AJM.
Cell 2015-04-23
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Widespread macromolecular interaction perturbations in human genetic disorders.

Authors: Authors: Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barabási AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M.
Cell 2015-04-23
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Protein domain-level landscape of cancer-type-specific somatic mutations.

Authors: Authors: Yang F, Petsalaki E, Rolland T, Hill DE, Vidal M, Roth FP.
PLoS Comput Biol 2015-03-01
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