
Matt Meyerson
Charles A. Dana Chair in Human Cancer Genetics, Dana-Farber Cancer Institute
Professor of Genetics and Medicine, Harvard Medical School
Director, Center for Cancer Genomics, Dana-Farber Cancer Institute
Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors.
Authors: Authors: Ji H, Zhao X, Yuza Y, Shimamura T, Li D, Protopopov A, Jung BL, McNamara K, Xia H, Glatt KA, Thomas RK, Sasaki H, Horner JW, Eck M, Mitchell A, Sun Y, Al-Hashem R, Bronson RT, Rabindran SK, Discafani CM, Maher E, Shapiro GI, Meyerson M, Wong KK.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays.
Authors: Authors: Beroukhim R, Lin M, Park Y, Hao K, Zhao X, Garraway LA, Fox EA, Hochberg EP, Mellinghoff IK, Hofer MD, Descazeaud A, Rubin MA, Meyerson M, Wong WH, Sellers WR, Li C.
PLoS Comput Biol
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PLoS Comput Biol
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Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor.
Authors: Authors: Alvarez JV, Greulich H, Sellers WR, Meyerson M, Frank DA.
Cancer Res
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Cancer Res
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A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening.
Authors: Authors: Jänne PA, Borras AM, Kuang Y, Rogers AM, Joshi VA, Liyanage H, Lindeman N, Lee JC, Halmos B, Maher EA, Distel RJ, Meyerson M, Johnson BE.
Clin Cancer Res
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Clin Cancer Res
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Allele-specific amplification in cancer revealed by SNP array analysis.
Authors: Authors: LaFramboise T, Weir BA, Zhao X, Beroukhim R, Li C, Harrington D, Sellers WR, Meyerson M.
PLoS Comput Biol
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PLoS Comput Biol
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Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants.
Authors: Authors: Greulich H, Chen TH, Feng W, Jänne PA, Alvarez JV, Zappaterra M, Bulmer SE, Frank DA, Hahn WC, Sellers WR, Meyerson M.
PLoS Med
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PLoS Med
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The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
Authors: Authors: Yokoyama A, Somervaille TC, Smith KS, Rozenblatt-Rosen O, Meyerson M, Cleary ML.
Cell
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Cell
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Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c.
Authors: Authors: Karnik SK, Hughes CM, Gu X, Rozenblatt-Rosen O, McLean GW, Xiong Y, Meyerson M, Kim SK.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Epidermal growth factor-independent transformation of Ba/F3 cells with cancer-derived epidermal growth factor receptor mutants induces gefitinib-sensitive cell cycle progression.
Authors: Authors: Jiang J, Greulich H, Jänne PA, Sellers WR, Meyerson M, Griffin JD.
Cancer Res
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Cancer Res
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An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor.
Authors: Authors: Kobayashi S, Ji H, Yuza Y, Meyerson M, Wong KK, Tenen DG, Halmos B.
Cancer Res
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Cancer Res
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