Matthew Warman headshot

Matthew L. Warman, M.D.

Professor of Genetics
617-919-2371
Matt Warman Website
Consequences of disease-causing mutations on lubricin protein synthesis, secretion, and post-translational processing.
Authors: Authors: Rhee DK, Marcelino J, Al-Mayouf S, Schelling DK, Bartels CF, Cui Y, Laxer R, Goldbach-Mansky R, Warman ML.
J Biol Chem
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Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling.
Authors: Authors: Ai M, Holmen SL, Van Hul W, Williams BO, Warman ML.
Mol Cell Biol
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Association of articular cartilage degradation and loss of boundary-lubricating ability of synovial fluid following injury and inflammatory arthritis.
Authors: Authors: Elsaid KA, Jay GD, Warman ML, Rhee DK, Chichester CO.
Arthritis Rheum
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The role of sequence variations within the genes encoding collagen II, IX and XI in non-syndromic, early-onset osteoarthritis.
Authors: Authors: Jakkula E, Melkoniemi M, Kiviranta I, Lohiniva J, Räinä SS, Perälä M, Warman ML, Ahonen K, Kröger H, Göring HH, Ala-Kokko L.
Osteoarthritis Cartilage
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The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth.
Authors: Authors: Rhee DK, Marcelino J, Baker M, Gong Y, Smits P, Lefebvre V, Jay GD, Stewart M, Wang H, Warman ML, Carpten JD.
J Clin Invest
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WISP3, the gene responsible for the human skeletal disease progressive pseudorheumatoid dysplasia, is not essential for skeletal function in mice.
Authors: Authors: Kutz WE, Gong Y, Warman ML.
Mol Cell Biol
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Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.
Authors: Authors: Holmen SL, Giambernardi TA, Zylstra CR, Buckner-Berghuis BD, Resau JH, Hess JF, Glatt V, Bouxsein ML, Ai M, Warman ML, Williams BO.
J Bone Miner Res
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Cohen syndrome in the Ohio Amish.
Authors: Authors: Falk MJ, Feiler HS, Neilson DE, Maxwell K, Lee JV, Segall SK, Robin NH, Wilhelmsen KC, Träskelin AL, Kolehmainen J, Lehesjoki AE, Wiznitzer M, Warman ML.
Am J Med Genet A
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Mutations in the transmembrane natriuretic peptide receptor NPR-B impair skeletal growth and cause acromesomelic dysplasia, type Maroteaux.
Authors: Authors: Bartels CF, Bükülmez H, Padayatti P, Rhee DK, van Ravenswaaij-Arts C, Pauli RM, Mundlos S, Chitayat D, Shih LY, Al-Gazali LI, Kant S, Cole T, Morton J, Cormier-Daire V, Faivre L, Lees M, Kirk J, Mortier GR, Leroy J, Zabel B, Kim CA, Crow Y, Braverman NE, van den Akker F, Warman ML.
Am J Hum Genet
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Autosomal dominant acute necrotizing encephalopathy maps to 2q12.1-2q13.
Authors: Authors: Neilson DE, Feiler HS, Wilhelmsen KC, Lynn A, Eiben RM, Kerr DS, Warman ML.
Ann Neurol
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