
Monica P. Colaiacovo, Ph.D.
Professor of Genetics, Harvard Medical School
Organization of the synaptonemal complex during meiosis in Caenorhabditis elegans.
Authors: Authors: Schild-Prüfert K, Saito TT, Smolikov S, Gu Y, Hincapie M, Hill DE, Vidal M, McDonald K, Colaiácovo MP.
Genetics
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Genetics
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SPR-5 is a histone H3K4 demethylase with a role in meiotic double-strand break repair.
Authors: Authors: Nottke AC, Beese-Sims SE, Pantalena LF, Reinke V, Shi Y, Colaiácovo MP.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Advances in imaging reveal novel insights into the mechanisms promoting accurate chromosome segregation in mitosis and meiosis.
Break to make a connection.
Mechanistic insights into the action of Bisphenol A on the germline using C. elegans.
Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities.
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage.
Authors: Authors: Chou DM, Adamson B, Dephoure NE, Tan X, Nottke AC, Hurov KE, Gygi SP, Colaiácovo MP, Elledge SJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.
Authors: Authors: Smogorzewska A, Desetty R, Saito TT, Schlabach M, Lach FP, Sowa ME, Clark AB, Kunkel TA, Harper JW, Colaiácovo MP, Elledge SJ.
Mol Cell
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Mol Cell
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Genetics: Crossover control in two steps.
Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates.
Authors: Authors: Saito TT, Youds JL, Boulton SJ, Colaiácovo MP.
PLoS Genet
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PLoS Genet
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