
Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by RNA-based isolation.
Authors: Authors: Amamoto R, Garcia MD, West ER, Choi J, Lapan SW, Lane EA, Perrimon N, Cepko CL.
Elife
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Elife
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Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species.
Authors: Authors: Parkhitko AA, Jouandin P, Mohr SE, Perrimon N.
Aging Cell
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Aging Cell
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Pooled CRISPR Screens in Drosophila Cells.
Authors: Authors: Viswanatha R, Brathwaite R, Hu Y, Li Z, Rodiger J, Merckaert P, Chung V, Mohr SE, Perrimon N.
Curr Protoc Mol Biol
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Curr Protoc Mol Biol
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An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms.
Authors: Authors: Kanca O, Zirin J, Garcia-Marques J, Knight SM, Yang-Zhou D, Amador G, Chung H, Zuo Z, Ma L, He Y, Lin WW, Fang Y, Ge M, Yamamoto S, Schulze KL, Hu Y, Spradling AC, Mohr SE, Perrimon N, Bellen HJ.
Elife
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Elife
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Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly.
Authors: Authors: Silver JT, Wirtz-Peitz F, Simões S, Pellikka M, Yan D, Binari R, Nishimura T, Li Y, Harris TJC, Perrimon N, Tepass U.
J Cell Biol
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J Cell Biol
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HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species.
Authors: Authors: Nicholson HE, Tariq Z, Housden BE, Jennings RB, Stransky LA, Perrimon N, Signoretti S, Kaelin WG.
Sci Signal
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Sci Signal
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Drosophila melanogaster: a simple system for understanding complexity.
The Multidimensional Organization of Interorgan Communication Networks.
Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells.
Authors: Authors: Zirin J, Ni X, Sack LM, Yang-Zhou D, Hu Y, Brathwaite R, Bulyk ML, Elledge SJ, Perrimon N.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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An Evolutionarily Conserved uORF Regulates PGC1a and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna.
Authors: Authors: Dumesic PA, Egan DF, Gut P, Tran MT, Parisi A, Chatterjee N, Jedrychowski M, Paschini M, Kazak L, Wilensky SE, Dou F, Bogoslavski D, Cartier JA, Perrimon N, Kajimura S, Parikh SM, Spiegelman BM.
Cell Metab
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Cell Metab
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