Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Gene Knock-Ins in Drosophila Using Homology-Independent Insertion of Universal Donor Plasmids.
A Drosophila model of oral peptide therapeutics for adult Intestinal Stem Cell tumors.
Authors: Authors: Bajpai A, Ahmad QT, Tang HW, Manzar N, Singh V, Thakur A, Ateeq B, Perrimon N, Sinha P.
Dis Model Mech
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Dis Model Mech
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The role of translationally controlled tumor protein in proliferation of Drosophila intestinal stem cells.
Authors: Authors: Kwon YV, Zhao B, Xu C, Lee J, Chen CL, Vinayagam A, Edgar BA, Perrimon N.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by RNA-based isolation.
Authors: Authors: Amamoto R, Garcia MD, West ER, Choi J, Lapan SW, Lane EA, Perrimon N, Cepko CL.
Elife
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Elife
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Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species.
Authors: Authors: Parkhitko AA, Jouandin P, Mohr SE, Perrimon N.
Aging Cell
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Aging Cell
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Pooled CRISPR Screens in Drosophila Cells.
Authors: Authors: Viswanatha R, Brathwaite R, Hu Y, Li Z, Rodiger J, Merckaert P, Chung V, Mohr SE, Perrimon N.
Curr Protoc Mol Biol
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Curr Protoc Mol Biol
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An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms.
Authors: Authors: Kanca O, Zirin J, Garcia-Marques J, Knight SM, Yang-Zhou D, Amador G, Chung H, Zuo Z, Ma L, He Y, Lin WW, Fang Y, Ge M, Yamamoto S, Schulze KL, Hu Y, Spradling AC, Mohr SE, Perrimon N, Bellen HJ.
Elife
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Elife
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Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly.
Authors: Authors: Silver JT, Wirtz-Peitz F, Simões S, Pellikka M, Yan D, Binari R, Nishimura T, Li Y, Harris TJC, Perrimon N, Tepass U.
J Cell Biol
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J Cell Biol
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HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species.
Authors: Authors: Nicholson HE, Tariq Z, Housden BE, Jennings RB, Stransky LA, Perrimon N, Signoretti S, Kaelin WG.
Sci Signal
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Sci Signal
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Drosophila melanogaster: a simple system for understanding complexity.