Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Optimized strategy for in vivo Cas9-activation in Drosophila.
Authors: Authors: Ewen-Campen B, Yang-Zhou D, Fernandes VR, González DP, Liu LP, Tao R, Ren X, Sun J, Hu Y, Zirin J, Mohr SE, Ni JQ, Perrimon N.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Gene2Function: An Integrated Online Resource for Gene Function Discovery.
Activin signaling mediates muscle-to-adipose communication in a mitochondria dysfunction-associated obesity model.
Authors: Authors: Song W, Owusu-Ansah E, Hu Y, Cheng D, Ni X, Zirin J, Perrimon N.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation.
Authors: Authors: Lee HJ, Jedrychowski MP, Vinayagam A, Wu N, Shyh-Chang N, Hu Y, Min-Wen C, Moore JK, Asara JM, Lyssiotis CA, Perrimon N, Gygi SP, Cantley LC, Kirschner MW.
Cell Rep
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Cell Rep
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Proximity-dependent labeling methods for proteomic profiling in living cells.
An Evolutionarily Conserved Role of Presenilin in Neuronal Protection in the Aging Drosophila Brain.
Open questions: completing the parts list and finding the integrating signals.
MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.
Authors: Authors: Wang J, Al-Ouran R, Hu Y, Kim SY, Wan YW, Wangler MF, Yamamoto S, Chao HT, Comjean A, Mohr SE, Perrimon N, Liu Z, Bellen HJ.
Am J Hum Genet
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Am J Hum Genet
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Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca2+ signaling in the Drosophila midgut.
Development of an optimized synthetic Notch receptor as an in vivo cell-cell contact sensor.