Norbert Perrimon headshot

Norbert Perrimon, Ph.D.

James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
617-432-7672
Perrimon Lab Website
Comparison of Cas9 activators in multiple species.
Authors: Authors: Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJK, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G.
Nat Methods
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Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila.
Authors: Authors: Parkhitko AA, Binari R, Zhang N, Asara JM, Demontis F, Perrimon N.
Genes Dev
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Comparing CRISPR and RNAi-based screening technologies.
Authors: Authors: Housden BE, Perrimon N.
Nat Biotechnol
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The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling.
Authors: Authors: Harris KP, Zhang YV, Piccioli ZD, Perrimon N, Littleton JT.
Elife
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Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets.
Authors: Authors: Vinayagam A, Gibson TE, Lee HJ, Yilmazel B, Roesel C, Hu Y, Kwon Y, Sharma A, Liu YY, Perrimon N, Barabási AL.
Proc Natl Acad Sci U S A
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miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga.
Authors: Authors: De Lella Ezcurra AL, Bertolin AP, Kim K, Katz MJ, Gándara L, Misra T, Luschnig S, Perrimon N, Melani M, Wappner P.
PLoS Genet
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Wildtype adult stem cells, unlike tumor cells, are resistant to cellular damages in Drosophila.
Authors: Authors: Ma M, Zhao H, Zhao H, Binari R, Perrimon N, Li Z.
Dev Biol
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Fruit flies on the front line: the translational impact of Drosophila.
Authors: Authors: Perrimon N, Bonini NM, Dhillon P.
Dis Model Mech
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A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.
Authors: Authors: Breitkopf SB, Yang X, Begley MJ, Kulkarni M, Chiu YH, Turke AB, Lauriol J, Yuan M, Qi J, Engelman JA, Hong P, Kontaridis MI, Cantley LC, Perrimon N, Asara JM.
Sci Rep
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Toward a Systems Understanding of Signaling Pathway Function.
Authors: Authors: Doupé DP, Perrimon N.
Curr Top Dev Biol
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