Norbert Perrimon headshot

Norbert Perrimon, Ph.D.

James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
617-432-7672
Perrimon Lab Website
Approaches to deorphanize secretome: Classical, computational, and next generation strategies to reveal ligand-receptor networks.
Authors: Authors: Han M, Perrimon N.
EXO
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Microproteins Simba1 and Simba2 activate Wingless signaling during the reactivation of neural stem cells in Drosophila.
Authors: Authors: Lin J, Deng Q, Gao Y, Tan YS, Zhong Z, Tan LKA, Tan BOP, Virshup DM, Bosch JA, Perrimon N, Wang H.
Nat Commun
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A Structure-Guided Kinase-Transcription Factor Interactome Atlas Reveals Docking Landscapes of the Kinome.
Authors: Authors: Kim AR, Huang K, Johnson JL, Yaron-Barir TM, Wang K, Cantley LC, Hu Y, Perrimon N.
bioRxiv
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A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes.
Authors: Authors: Mameli E, Samantsidis GR, Viswanatha R, Kwon H, Hall DR, Butnaru M, Hu Y, Mohr SE, Perrimon N, Smith RC.
Nat Commun
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Desaturase-dependent secretory functions of hepatocyte-like cells control systemic lipid metabolism during starvation in Drosophila.
Authors: Authors: Li J, Huang K, Dibra I, Liu Y, Perrimon N, Simons M.
Nat Commun
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Phage display-mediated immuno-PCR to detect low-abundance secreted proteins in Drosophila.
Authors: Authors: Han M, Xia B, Kim AR, Filine E, Stoneburner E, Miao T, Liu Y, Zirin J, Perrimon N.
bioRxiv
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Hepatic ceramide synthesis links systemic inflammation to organelle dysfunction in cancer.
Authors: Authors: Liu Y, Miao T, Wang A, Dantas E, Kim AR, Zhang Z, Sun X, Binari R, Asara JM, Hu Y, Goncalves MD, Janowitz T, Perrimon N.
bioRxiv
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A family of lethal exotoxins defined by cell entry via the Attractin receptor.
Authors: Authors: Viswanatha R, Lee D, Robins WR, Mameli E, Hu Y, Kim AR, Hashmi Y, Nishida H, Prakash G, Butnaru M, Churchman S, Mohr SE, Mekalanos JJ, Perrimon N.
bioRxiv
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The epigenetic factor Zrf1 regulates intestinal stem cell proliferation during midgut regeneration.
Authors: Authors: Shun Li JS, Liu Y, Kim AR, Qadiri M, Xu J, Xia B, Binari R, Asara JM, Hu Y, Perrimon N.
PLoS Genet
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In-situ glial cell-surface proteomics identifies pro-longevity factors in Drosophila.
Authors: Authors: Marques MP, Sun B, Park YJ, Jackson T, Lu TC, Qi Y, Harrison E, Wang MC, Venkatachalam K, Pasha OM, Varanasi A, Carey DK, Mani DR, Zirin J, Qadiri M, Hu Y, Perrimon N, Carr SA, Udeshi ND, Luo L, Li J, Li H.
bioRxiv
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