Norbert Perrimon headshot

Norbert Perrimon, Ph.D.

James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
617-432-7672
Perrimon Lab Website
Metabolic command centers in Drosophila: how the fat body and oenocytes orchestrate immunity, reproduction, and aging.
Authors: Authors: Huang K, Perrimon N.
Curr Opin Insect Sci
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The Drosophila proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth.
Authors: Authors: Ewen-Campen B, Chen W, Tattikota SG, Liu Y, Hu Y, Perrimon N.
Nat Commun
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Modeling tissue-specific Drosophila metabolism identifies high sugar diet-induced metabolic dysregulation in muscle at reaction and pathway levels.
Authors: Authors: Moon SJ, Hu Y, Dzieciatkowska M, Kim AR, Asara JM, D'Alessandro A, Perrimon N.
Nat Commun
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Expression Atlas in 2026: enabling FAIR and open expression data through community collaboration and integration.
Authors: Authors: Madrigal P, Thanki AS, Fexova S, Yu ID, Chatzigeorgiou A, Zucchi I, Marugan Calles JC, Vilmovsky L, Khen A, Zhao L, Erdos K, Kurri SR, Selvakumar S, Kumbham U, Prakash A, Wang S, Green A, Ribas CE, Sweeney B, Alegbe T, Suveges D, Hemrom A, Gomez Gutierrez DE, Insua S, Jeffryes M, Pearce M, Basutkar P, Kaforou M, Cunnington A, Levin M, Kumari S, Ware D, Goutte-Gattat D, Röper K, Brown NH, Hu Y, Perrimon N, Papatheodorou I, Brazma A, Hermjakob H, Harrison M, Ocaña D, Ochoa D, McDonagh EM, Bateman A, Keane T, Vizcaíno JA, Ernst C.
Nucleic Acids Res
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Approaches to deorphanize secretome: Classical, computational, and next generation strategies to reveal ligand-receptor networks.
Authors: Authors: Han M, Perrimon N.
EXO
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Microproteins Simba1 and Simba2 activate Wingless signaling during the reactivation of neural stem cells in Drosophila.
Authors: Authors: Lin J, Deng Q, Gao Y, Tan YS, Zhong Z, Tan LKA, Tan BOP, Virshup DM, Bosch JA, Perrimon N, Wang H.
Nat Commun
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A Structure-Guided Kinase-Transcription Factor Interactome Atlas Reveals Docking Landscapes of the Kinome.
Authors: Authors: Kim AR, Huang K, Johnson JL, Yaron-Barir TM, Wang K, Cantley LC, Hu Y, Perrimon N.
bioRxiv
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A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes.
Authors: Authors: Mameli E, Samantsidis GR, Viswanatha R, Kwon H, Hall DR, Butnaru M, Hu Y, Mohr SE, Perrimon N, Smith RC.
Nat Commun
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Desaturase-dependent secretory functions of hepatocyte-like cells control systemic lipid metabolism during starvation in Drosophila.
Authors: Authors: Li J, Huang K, Dibra I, Liu Y, Perrimon N, Simons M.
Nat Commun
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Phage display-mediated immuno-PCR to detect low-abundance secreted proteins in Drosophila.
Authors: Authors: Han M, Xia B, Kim AR, Filine E, Stoneburner E, Miao T, Liu Y, Zirin J, Perrimon N.
bioRxiv
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