Norbert Perrimon

Norbert Perrimon, Ph.D.

James Stillman Professor of Developmental Biology

617-432-7672

Publications

mTORC1 promotes cell growth via m6A-dependent mRNA degradation.

Authors: Authors: Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, Mathur L, Kim SS, Jung S, Tang HW, Monette S, Rabinowitz JD, Perrimon N, Jaffrey SR, Blenis J.
Mol Cell 2021-05-20
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Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes.

Authors: Authors: Feng X, López Del Amo V, Mameli E, Lee M, Bishop AL, Perrimon N, Gantz VM.
Nat Commun 2021-05-20
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Proteomics of protein trafficking by in vivo tissue-specific labeling.

Authors: Authors: Droujinine IA, Meyer AS, Wang D, Udeshi ND, Hu Y, Rocco D, McMahon JA, Yang R, Guo J, Mu L, Carey DK, Svinkina T, Zeng R, Branon T, Tabatabai A, Bosch JA, Asara JM, Ting AY, Carr SA, McMahon AP, Perrimon N.
Nat Commun 2021-04-22
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Methods and tools for spatial mapping of single-cell RNAseq clusters in Drosophila.

Authors: Authors: Mohr SE, Tattikota SG, Xu J, Zirin J, Hu Y, Perrimon N.
Genetics 2021-04-15
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mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy.

Authors: Authors: Tang HW, Weng JH, Lee WX, Hu Y, Gu L, Cho S, Lee G, Binari R, Li C, Cheng ME, Kim AR, Xu J, Shen Z, Xu C, Asara JM, Blenis J, Perrimon N.
Proc Natl Acad Sci U S A 2021-03-09
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Defining cell types and lineage in the Drosophila midgut using single cell transcriptomics.

Authors: Authors: Hung RJ, Li JSS, Liu Y, Perrimon N.
Curr Opin Insect Sci 2021-02-17
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Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells.

Authors: Authors: Parkhitko AA, Singh A, Hsieh S, Hu Y, Binari R, Lord CJ, Hannenhalli S, Ryan CJ, Perrimon N.
PLoS Genet 2021-02-01
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Correction: Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity.

Authors: Authors: Ghosh AC, Tattikota SG, Liu Y, Comjean A, Hu Y, Barrera V, Ho Sui SJ, Perrimon N.
Elife 2021-01-21
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Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.

Authors: Authors: Wang W, Li J, Tan J, Wang M, Yang J, Zhang ZM, Li C, Basnakian AG, Tang HW, Perrimon N, Zhou Q.
Nat Commun 2021-01-20
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FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update.

Authors: Authors: Hu Y, Comjean A, Rodiger J, Liu Y, Gao Y, Chung V, Zirin J, Perrimon N, Mohr SE.
Nucleic Acids Res 2021-01-08
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