Norbert Perrimon headshot

Norbert Perrimon, Ph.D.

James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
617-432-7672
Perrimon Lab Website
Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch.
Authors: Authors: Gordon WR, Zimmerman B, He L, Miles LJ, Huang J, Tiyanont K, McArthur DG, Aster JC, Perrimon N, Loparo JJ, Blacklow SC.
Dev Cell
View full abstract on Pubmed
A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs.
Authors: Authors: Fulga TA, McNeill EM, Binari R, Yelick J, Blanche A, Booker M, Steinkraus BR, Schnall-Levin M, Zhao Y, DeLuca T, Bejarano F, Han Z, Lai EC, Wall DP, Perrimon N, Van Vactor D.
Nat Commun
View full abstract on Pubmed
Systemic organ wasting induced by localized expression of the secreted insulin/IGF antagonist ImpL2.
Authors: Authors: Kwon Y, Song W, Droujinine IA, Hu Y, Asara JM, Perrimon N.
Dev Cell
View full abstract on Pubmed
Highly efficient Cas9-mediated transcriptional programming.
Authors: Authors: Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM.
Nat Methods
View full abstract on Pubmed
A systems-level interrogation identifies regulators of Drosophila blood cell number and survival.
Authors: Authors: Sopko R, Lin YB, Makhijani K, Alexander B, Perrimon N, Brückner K.
PLoS Genet
View full abstract on Pubmed
Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices.
Authors: Authors: Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Regulators of autophagosome formation in Drosophila muscles.
Authors: Authors: Zirin J, Nieuwenhuis J, Samsonova A, Tao R, Perrimon N.
PLoS Genet
View full abstract on Pubmed
Stress signaling between organs in metazoa.
Authors: Authors: Owusu-Ansah E, Perrimon N.
Annu Rev Cell Dev Biol
View full abstract on Pubmed
GLAD: an Online Database of Gene List Annotation for Drosophila.
Authors: Authors: Hu Y, Comjean A, Perkins LA, Perrimon N, Mohr SE.
J Genomics
View full abstract on Pubmed
Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos.
Authors: Authors: Sopko R, Foos M, Vinayagam A, Zhai B, Binari R, Hu Y, Randklev S, Perkins LA, Gygi SP, Perrimon N.
Dev Cell
View full abstract on Pubmed