
Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Matter arising: off-targets and genome-scale RNAi screens in Drosophila.
Design and implementation of high-throughput RNAi screens in cultured Drosophila cells.
Authors: Authors: Ramadan N, Flockhart I, Booker M, Perrimon N, Mathey-Prevot B.
Nat Protoc
View full abstract on Pubmed
Nat Protoc
View full abstract on Pubmed
Applications of high-throughput RNA interference screens to problems in cell and developmental biology.
A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila.
Authors: Authors: DasGupta R, Nybakken K, Booker M, Mathey-Prevot B, Gonsalves F, Changkakoty B, Perrimon N.
Genome Biol
View full abstract on Pubmed
Genome Biol
View full abstract on Pubmed
A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling.
High-throughput approaches to dissecting MAPK signaling pathways.
Minimizing the risk of reporting false positives in large-scale RNAi screens.
Authors: Authors: Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prévôt B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R.
Nat Methods
View full abstract on Pubmed
Nat Methods
View full abstract on Pubmed
COPI activity coupled with fatty acid biosynthesis is required for viral replication.
Authors: Authors: Cherry S, Kunte A, Wang H, Coyne C, Rawson RB, Perrimon N.
PLoS Pathog
View full abstract on Pubmed
PLoS Pathog
View full abstract on Pubmed
Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays.
Authors: Authors: Kulkarni MM, Booker M, Silver SJ, Friedman A, Hong P, Perrimon N, Mathey-Prevot B.
Nat Methods
View full abstract on Pubmed
Nat Methods
View full abstract on Pubmed
The emergence of geometric order in proliferating metazoan epithelia.