Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Super-size flies.
Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity.
Authors: Authors: Hayward P, Brennan K, Sanders P, Balayo T, DasGupta R, Perrimon N, Martinez Arias A.
Development
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Development
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Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing.
Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition.
Authors: Authors: Cherry S, Doukas T, Armknecht S, Whelan S, Wang H, Sarnow P, Perrimon N.
Genes Dev
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Genes Dev
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High-throughput RNA interference screens in Drosophila tissue culture cells.
Authors: Authors: Armknecht S, Boutros M, Kiger A, Nybakken K, Mathey-Prevot B, Perrimon N.
Methods Enzymol
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Methods Enzymol
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Towards automated cellular image segmentation for RNAi genome-wide screening.
Authors: Authors: Zhou X, Liu KY, Bradley P, Perrimon N, Wong ST.
Med Image Comput Comput Assist Interv
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Med Image Comput Comput Assist Interv
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The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors.
Authors: Authors: Baeg GH, Selva EM, Goodman RM, Dasgupta R, Perrimon N.
Dev Biol
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Dev Biol
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Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets.
Authors: Authors: Eggert US, Kiger AA, Richter C, Perlman ZE, Perrimon N, Mitchison TJ, Field CM.
PLoS Biol
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PLoS Biol
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Using RNAi to catch Drosophila genes in a web of interactions: insights into cancer research.
Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila.
Authors: Authors: Schlesinger A, Kiger A, Perrimon N, Shilo BZ.
Dev Cell
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Dev Cell
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