Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Genetic screening for signal transduction in the era of network biology.
Applications of high-throughput RNA interference screens to problems in cell and developmental biology.
A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila.
Authors: Authors: DasGupta R, Nybakken K, Booker M, Mathey-Prevot B, Gonsalves F, Changkakoty B, Perrimon N.
Genome Biol
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Genome Biol
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GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo.
Authors: Authors: Bach EA, Ekas LA, Ayala-Camargo A, Flaherty MS, Lee H, Perrimon N, Baeg GH.
Gene Expr Patterns
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Gene Expr Patterns
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Drug-target identification in Drosophila cells: combining high-throughout RNAi and small-molecule screens.
Authors: Authors: Perrimon N, Friedman A, Mathey-Prevot B, Eggert US.
Drug Discov Today
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Drug Discov Today
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Matter arising: off-targets and genome-scale RNAi screens in Drosophila.
Design and implementation of high-throughput RNAi screens in cultured Drosophila cells.
Authors: Authors: Ramadan N, Flockhart I, Booker M, Perrimon N, Mathey-Prevot B.
Nat Protoc
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Nat Protoc
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A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling.
High-throughput approaches to dissecting MAPK signaling pathways.
COPI activity coupled with fatty acid biosynthesis is required for viral replication.
Authors: Authors: Cherry S, Kunte A, Wang H, Coyne C, Rawson RB, Perrimon N.
PLoS Pathog
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PLoS Pathog
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