Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs.
Dissection of the Torso signal transduction pathway in Drosophila.
Authors: Authors: Perrimon N, Lu X, Hou XS, Hsu JC, Melnick MB, Chou TB, Perkins LA.
Mol Reprod Dev
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Mol Reprod Dev
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The porcupine gene is required for wingless autoregulation in Drosophila.
Authors: Authors: Manoukian AS, Yoffe KB, Wilder EL, Perrimon N.
Development
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Development
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Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.
Authors: Authors: Sokol SY, Klingensmith J, Perrimon N, Itoh K.
Development
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Development
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A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist.
Authors: Authors: Yin JC, Wallach JS, Wilder EL, Klingensmith J, Dang D, Perrimon N, Zhou H, Tully T, Quinn WG.
Mol Cell Biol
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Mol Cell Biol
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Evidence for engrailed-independent wingless autoregulation in Drosophila.
Authors: Authors: Yoffe KB, Manoukian AS, Wilder EL, Brand AH, Perrimon N.
Dev Biol
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Dev Biol
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Activation of posterior gap gene expression in the Drosophila blastoderm.
Authors: Authors: Rivera-Pomar R, Lu X, Perrimon N, Taubert H, Jäckle H.
Nature
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Nature
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Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.
Authors: Authors: Harrison DA, Binari R, Nahreini TS, Gilman M, Perrimon N.
EMBO J
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EMBO J
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Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.
Authors: Authors: Sokol SY, Klingensmith J, Perrimon N, Itoh K.
Development
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Development
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The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway.