Peter Sicinski headshot

Peter Sicinski, Ph.D., M.D.

Professor of Genetics
617-632-5005
Sicinski Lab Website
Author Correction: Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.
Authors: Authors: Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ, Sicinski P, Wei W.
Nature
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Kinase-independent function of E-type cyclins in liver cancer.
Authors: Authors: Geng Y, Michowski W, Chick JM, Wang YE, Jecrois ME, Sweeney KE, Liu L, Han RC, Ke N, Zagozdzon A, Sicinska E, Bronson RT, Gygi SP, Sicinski P.
Proc Natl Acad Sci U S A
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Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit.
Authors: Authors: Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P.
Proc Natl Acad Sci U S A
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Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers.
Authors: Authors: Hydbring P, Wang Y, Fassl A, Li X, Matia V, Otto T, Choi YJ, Sweeney KE, Suski JM, Yin H, Bogorad RL, Goel S, Yuzugullu H, Kauffman KJ, Yang J, Jin C, Li Y, Floris D, Swanson R, Ng K, Sicinska E, Anders L, Zhao JJ, Polyak K, Anderson DG, Li C, Sicinski P.
Cancer Cell
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A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2.
Authors: Authors: Zhou J, Tien AC, Alberta JA, Ficarro SB, Griveau A, Sun Y, Deshpande JS, Card JD, Morgan-Smith M, Michowski W, Hashizume R, James CD, Ligon KL, Snider WD, Sicinski P, Marto JA, Rowitch DH, Stiles CD.
Cell Rep
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D-cyclins repress apoptosis in hematopoietic cells by controlling death receptor Fas and its ligand FasL.
Authors: Authors: Choi YJ, Saez B, Anders L, Hydbring P, Stefano J, Bacon NA, Cook C, Kalaszczynska I, Signoretti S, Young RA, Scadden DT, Sicinski P.
Dev Cell
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Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis.
Authors: Authors: Martinerie L, Manterola M, Chung SS, Panigrahi SK, Weisbach M, Vasileva A, Geng Y, Sicinski P, Wolgemuth DJ.
PLoS Genet
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Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.
Authors: Authors: Cole AM, Myant K, Reed KR, Ridgway RA, Athineos D, Van den Brink GR, Muncan V, Clevers H, Clarke AR, Sicinski P, Sansom OJ.
Cancer Res
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Roles of cyclins A and E in induction of centrosome amplification in p53-compromised cells.
Authors: Authors: Hanashiro K, Kanai M, Geng Y, Sicinski P, Fukasawa K.
Oncogene
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Peroxisome proliferator-activated receptor-delta induces cell proliferation by a cyclin E1-dependent mechanism and is up-regulated in thyroid tumors.
Authors: Authors: Zeng L, Geng Y, Tretiakova M, Yu X, Sicinski P, Kroll TG.
Cancer Res
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