Raju Kucherlapati headshot

Raju Kucherlapati, Ph.D.

Paul C. Cabot Professor of Genetics, Harvard Medical School
617-525-4445
Kucherlapati Lab Website
Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes.
Authors: Authors: Dragileva E, Hendricks A, Teed A, Gillis T, Lopez ET, Friedberg EC, Kucherlapati R, Edelmann W, Lunetta KL, MacDonald ME, Wheeler VC.
Neurobiol Dis
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Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice.
Authors: Authors: Gravaghi C, Bo J, Laperle KM, Quimby F, Kucherlapati R, Edelmann W, Lamprecht SA.
Int J Obes (Lond)
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Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.
Authors: Authors: Kucherlapati MH, Yang K, Fan K, Kuraguchi M, Sonkin D, Rosulek A, Lipkin M, Bronson RT, Aronow BJ, Kucherlapati R.
Proc Natl Acad Sci U S A
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PolyPhred analysis software for mutation detection from fluorescence-based sequence data.
Authors: Authors: Montgomery KT, Iartchouck O, Li L, Loomis S, Obourn V, Kucherlapati R.
Curr Protoc Hum Genet
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Dietary calcium and cholecalciferol modulate cyclin D1 expression, apoptosis, and tumorigenesis in intestine of adenomatous polyposis coli1638N/+ mice.
Authors: Authors: Yang K, Lamprecht SA, Shinozaki H, Fan K, Yang W, Newmark HL, Kopelovich L, Edelmann W, Jin B, Gravaghi C, Augenlicht L, Kucherlapati R, Lipkin M.
J Nutr
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Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations.
Authors: Authors: Barrera-Oro J, Liu TY, Gorden E, Kucherlapati R, Shao C, Tischfield JA.
Mutat Res
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Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.
Authors: Authors: Chen PC, Kuraguchi M, Velasquez J, Wang Y, Yang K, Edwards R, Gillen D, Edelmann W, Kucherlapati R, Lipkin SM.
PLoS Genet
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Genetics and genomics in the practice of medicine.
Authors: Authors: Joshi VA, Kucherlapati R.
Gastroenterology
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Shared genetic causes of cardiac hypertrophy in children and adults.
Authors: Authors: Morita H, Rehm HL, Menesses A, McDonough B, Roberts AE, Kucherlapati R, Towbin JA, Seidman JG, Seidman CE.
N Engl J Med
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Mutation frequencies and spectra in DNA polymerase eta-deficient mice.
Authors: Authors: Busuttil RA, Lin Q, Stambrook PJ, Kucherlapati R, Vijg J.
Cancer Res
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