Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Elledge Lab Website

Additional Websites
Publications

HHMI Investigator

Taking the brakes off telomerase.

Authors: Authors: Naxerova K, Elledge SJ.
Elife 2015-07-21
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A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors.

Authors: Authors: Izhar L, Adamson B, Ciccia A, Lewis J, Pontano-Vaites L, Leng Y, Liang AC, Westbrook TF, Harper JW, Elledge SJ.
Cell Rep 2015-06-09
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Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome.

Authors: Authors: Xu GJ, Kula T, Xu Q, Li MZ, Vernon SD, Ndung'u T, Ruxrungtham K, Sanchez J, Brander C, Chung RT, O'Connor KC, Walker B, Larman HB, Elledge SJ.
Science 2015-06-05
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NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis.

Authors: Authors: Gao J, Kim HM, Elia AE, Elledge SJ, Colaiácovo MP.
PLoS Genet 2015-03-01
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Homologous-recombination-deficient tumours are dependent on Pol?-mediated repair.

Authors: Authors: Ceccaldi R, Liu JC, Amunugama R, Hajdu I, Primack B, Petalcorin MI, O'Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D'Andrea AD.
Nature 2015-02-12
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Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response.

Authors: Authors: Ciccia A, Huang JW, Izhar L, Sowa ME, Harper JW, Elledge SJ.
Proc Natl Acad Sci U S A 2014-12-30
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DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.

Authors: Authors: Wang R, Persky NS, Yoo B, Ouerfelli O, Smogorzewska A, Elledge SJ, Pavletich NP.
Science 2014-11-28
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RNAi-based functional selection identifies novel cell migration determinants dependent on PI3K and AKT pathways.

Authors: Authors: Seo M, Lee S, Kim JH, Lee WH, Hu G, Elledge SJ, Suk K.
Nat Commun 2014-10-28
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Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents.

Authors: Authors: Zhu J, Davoli T, Perriera JM, Chin CR, Gaiha GD, John SP, Sigiollot FD, Gao G, Xu Q, Qu H, Pertel T, Sims JS, Smith JA, Baker RE, Maranda L, Ng A, Elledge SJ, Brass AL.
Cell Rep 2014-10-23
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Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10.

Authors: Authors: Finton KA, Friend D, Jaffe J, Gewe M, Holmes MA, Larman HB, Stuart A, Larimore K, Greenberg PD, Elledge SJ, Stamatatos L, Strong RK.
PLoS Pathog 2014-09-01
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