Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Additional Websites
Publications

DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.

Authors: Authors: Wang R, Persky NS, Yoo B, Ouerfelli O, Smogorzewska A, Elledge SJ, Pavletich NP.
Science 2014-11-28
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RNAi-based functional selection identifies novel cell migration determinants dependent on PI3K and AKT pathways.

Authors: Authors: Seo M, Lee S, Kim JH, Lee WH, Hu G, Elledge SJ, Suk K.
Nat Commun 2014-10-28
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Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents.

Authors: Authors: Zhu J, Davoli T, Perriera JM, Chin CR, Gaiha GD, John SP, Sigiollot FD, Gao G, Xu Q, Qu H, Pertel T, Sims JS, Smith JA, Baker RE, Maranda L, Ng A, Elledge SJ, Brass AL.
Cell Rep 2014-10-23
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Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10.

Authors: Authors: Finton KA, Friend D, Jaffe J, Gewe M, Holmes MA, Larman HB, Stuart A, Larimore K, Greenberg PD, Elledge SJ, Stamatatos L, Strong RK.
PLoS Pathog 2014-09-01
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Ronald R. Tasker Young Investigator Award 165 Promoting Endogenous GABAergic Analgesia via Kinase Modulation of Neuronal Ion Plasticity.

Authors: Authors: Kahle KT, Gao G, Zhang J, Latremoliere A, Andrews N, Shang Y, Alessi D, Woolf C, Elledge S, Clapham D.
Neurosurgery 2014-08-01
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GLTSCR2/PICT1 links mitochondrial stress and Myc signaling.

Authors: Authors: Yoon JC, Ling AJ, Isik M, Lee DY, Steinbaugh MJ, Sack LM, Boduch AN, Blackwell TK, Sinclair DA, Elledge SJ.
Proc Natl Acad Sci U S A 2014-03-11
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Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma.

Authors: Authors: Li J, Zhu S, Kozono D, Ng K, Futalan D, Shen Y, Akers JC, Steed T, Kushwaha D, Schlabach M, Carter BS, Kwon CH, Furnari F, Cavenee W, Elledge S, Chen CC.
Oncotarget 2014-02-28
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Chlamydia trachomatis-induced alterations in the host cell proteome are required for intracellular growth.

Authors: Authors: Olive AJ, Haff MG, Emanuele MJ, Sack LM, Barker JR, Elledge SJ, Starnbach MN.
Cell Host Microbe 2014-01-15
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Discovery of protein interactions using parallel analysis of translated ORFs (PLATO).

Authors: Authors: Larman HB, Liang AC, Elledge SJ, Zhu J.
Nat Protoc 2014-01-01
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When noise makes music: HIV reactivation with transcriptional noise enhancers.

Authors: Authors: Tan X, Elledge SJ.
Genome Med 2014-01-01
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