Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis.
Authors: Authors: Tian Q, Taupin J, Elledge S, Robertson M, Anderson P.
J Exp Med
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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control.
Authors: Authors: Deng C, Zhang P, Harper JW, Elledge SJ, Leder P.
Cell
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Cyclin D1 provides a link between development and oncogenesis in the retina and breast.
Authors: Authors: Sicinski P, Donaher JL, Parker SB, Li T, Fazeli A, Gardner H, Haslam SZ, Bronson RT, Elledge SJ, Weinberg RA.
Cell
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Stopped for repairs.
Authors: Authors: Sanchez Y, Elledge SJ.
Bioessays
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Inhibition of cyclin-dependent kinases by p21.
Authors: Authors: Harper JW, Elledge SJ, Keyomarsi K, Dynlacht B, Tsai LH, Zhang P, Dobrowolski S, Bai C, Connell-Crowley L, Swindell E, et al.
Mol Biol Cell
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p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
Authors: Authors: Matsuoka S, Edwards MC, Bai C, Parker S, Zhang P, Baldini A, Harper JW, Elledge SJ.
Genes Dev
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p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells.
Authors: Authors: Parker SB, Eichele G, Zhang P, Rawls A, Sands AT, Bradley A, Olson EN, Harper JW, Elledge SJ.
Science
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Ran-binding protein-1 is an essential component of the Ran/RCC1 molecular switch system in budding yeast.
Authors: Authors: Ouspenski II, Mueller UW, Matynia A, Sazer S, Elledge SJ, Brinkley BR.
J Biol Chem
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Hepatitis B virus X protein interacts with a probable cellular DNA repair protein.
Authors: Authors: Lee TH, Elledge SJ, Butel JS.
J Virol
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PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system.
Authors: Authors: Staudinger J, Zhou J, Burgess R, Elledge SJ, Olson EN.
J Cell Biol
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