Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1.
Authors: Authors: Zhang XF, Settleman J, Kyriakis JM, Takeuchi-Suzuki E, Elledge SJ, Marshall MS, Bruder JT, Rapp UR, Avruch J.
Nature
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Amplification of cyclin genes in colorectal carcinomas.
Authors: Authors: Leach FS, Elledge SJ, Sherr CJ, Willson JK, Markowitz S, Kinzler KW, Vogelstein B.
Cancer Res
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DNA damage and cell cycle regulation of ribonucleotide reductase.
Authors: Authors: Elledge SJ, Zhou Z, Allen JB, Navas TA.
Bioessays
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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.
Authors: Authors: Durfee T, Becherer K, Chen PL, Yeh SH, Yang Y, Kilburn AE, Lee WH, Elledge SJ.
Genes Dev
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Interactions among vertebrate helix-loop-helix proteins in yeast using the two-hybrid system.
Authors: Authors: Staudinger J, Perry M, Elledge SJ, Olson EN.
J Biol Chem
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Dominant genetics using a yeast genomic library under the control of a strong inducible promoter.
Authors: Authors: Ramer SW, Elledge SJ, Davis RW.
Proc Natl Acad Sci U S A
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Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle.
Authors: Authors: Koff A, Giordano A, Desai D, Yamashita K, Harper JW, Elledge S, Nishimoto T, Morgan DO, Franza BR, Roberts JM.
Science
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Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae.
Authors: Authors: Zhou Z, Elledge SJ.
Genetics
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CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle.
Authors: Authors: Elledge SJ, Richman R, Hall FL, Williams RT, Lodgson N, Harper JW.
Proc Natl Acad Sci U S A
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Ribonucleotide reductase: regulation, regulation, regulation.
Authors: Authors: Elledge SJ, Zhou Z, Allen JB.
Trends Biochem Sci
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