Steven McCarroll headshot

Steven A. McCarroll, Ph.D.

Dorothy and Milton Flier Professor of Biomedical Science and Genetics, Harvard Medical School
Director of Genomic Neurobiology, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard
617-432-7794
McCarroll Lab Website
Key Roles of CACNA1C/Cav1.2 and CALB1/Calbindin in Prefrontal Neurons Altered in Cognitive Disorders.
Authors: Authors: Datta D, Yang S, Joyce MKP, Woo E, McCarroll SA, Gonzalez-Burgos G, Perone I, Uchendu S, Ling E, Goldman M, Berretta S, Murray J, Morozov Y, Arellano J, Duque A, Rakic P, O'Dell R, van Dyck CH, Lewis DA, Wang M, Krienen FM, Arnsten AFT.
JAMA Psychiatry
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Protein-altering variants at copy number-variable regions influence diverse human phenotypes.
Authors: Authors: Hujoel MLA, Handsaker RE, Sherman MA, Kamitaki N, Barton AR, Mukamel RE, Terao C, McCarroll SA, Loh PR.
Nat Genet
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CSMD1 regulates brain complement activity and circuit development.
Authors: Authors: Baum ML, Wilton DK, Fox RG, Carey A, Hsu YH, Hu R, Jäntti HJ, Fahey JB, Muthukumar AK, Salla N, Crotty W, Scott-Hewitt N, Bien E, Sabatini DA, Lanser TB, Frouin A, Gergits F, Håvik B, Gialeli C, Nacu E, Lage K, Blom AM, Eggan K, McCarroll SA, Johnson MB, Stevens B.
Brain Behav Immun
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Modeling interpretable correspondence between cell state and perturbation response with CellCap.
Authors: Authors: Xu Y, Fleming S, Tegtmeyer M, McCarroll SA, Babadi M.
bioRxiv
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A concerted neuron-astrocyte program declines in ageing and schizophrenia.
Authors: Authors: Ling E, Nemesh J, Goldman M, Kamitaki N, Reed N, Handsaker RE, Genovese G, Vogelgsang JS, Gerges S, Kashin S, Ghosh S, Esposito JM, Morris K, Meyer D, Lutservitz A, Mullally CD, Wysoker A, Spina L, Neumann A, Hogan M, Ichihara K, Berretta S, McCarroll SA.
Nature
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Concerted neuron-astrocyte gene expression declines in aging and schizophrenia.
Authors: Authors: Ling E, Nemesh J, Goldman M, Kamitaki N, Reed N, Handsaker RE, Genovese G, Vogelgsang JS, Gerges S, Kashin S, Ghosh S, Esposito JM, French K, Meyer D, Lutservitz A, Mullally CD, Wysoker A, Spina L, Neumann A, Hogan M, Ichihara K, Berretta S, McCarroll SA.
bioRxiv
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High-dimensional phenotyping to define the genetic basis of cellular morphology.
Authors: Authors: Tegtmeyer M, Arora J, Asgari S, Cimini BA, Nadig A, Peirent E, Liyanage D, Way GP, Weisbart E, Nathan A, Amariuta T, Eggan K, Haghighi M, McCarroll SA, O'Connor L, Carpenter AE, Singh S, Nehme R, Raychaudhuri S.
Nat Commun
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BCFtools/liftover: an accurate and comprehensive tool to convert genetic variants across genome assemblies.
Authors: Authors: Genovese G, Rockweiler NB, Gorman BR, Bigdeli TB, Pato MT, Pato CN, Ichihara K, McCarroll SA.
Bioinformatics
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Author Correction: Conserved and divergent gene regulatory programs of the mammalian neocortex.
Authors: Authors: Zemke NR, Armand EJ, Wang W, Lee S, Zhou J, Li YE, Liu H, Tian W, Nery JR, Castanon RG, Bartlett A, Osteen JK, Li D, Zhuo X, Xu V, Chang L, Dong K, Indralingam HS, Rink JA, Xie Y, Miller M, Krienen FM, Zhang Q, Taskin N, Ting J, Feng G, McCarroll SA, Callaway EM, Wang T, Lein ES, Behrens MM, Ecker JR, Ren B.
Nature
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Conserved and divergent gene regulatory programs of the mammalian neocortex.
Authors: Authors: Zemke NR, Armand EJ, Wang W, Lee S, Zhou J, Li YE, Liu H, Tian W, Nery JR, Castanon RG, Bartlett A, Osteen JK, Li D, Zhuo X, Xu V, Chang L, Dong K, Indralingam HS, Rink JA, Xie Y, Miller M, Krienen FM, Zhang Q, Taskin N, Ting J, Feng G, McCarroll SA, Callaway EM, Wang T, Lein ES, Behrens MM, Ecker JR, Ren B.
Nature
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