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George Church, Ph.D.

hafoe: an interactive tool for the analysis of chimeric AAV libraries after random mutagenesis.
Authors: Authors: Jalatyan T, Aznauryan E, Hasan R, Vardanyan V, Nersisyan S, Thompson DB, Davidsohn N, Thomas S, van Haren S, Tam J, Milanova D, Church GM, Nersisyan L.
Gene Ther
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A diverse single-stranded DNA-annealing protein library enables efficient genome editing across bacterial phyla.
Authors: Authors: Filsinger GT, Mychack A, Lyerly E, Henriksen C, Bartlett TM, Kuchwara H, Eitzinger S, Bernhardt TG, Walker S, Church GM, Wannier TM.
Proc Natl Acad Sci U S A
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High-Throughput Extracellular Vesicle Isolation Using Plate-Based Size Exclusion Chromatography and Automation.
Authors: Authors: Gilboa T, Ter-Ovanesyan D, Babila CM, Whiteman S, Morton S, Kalish D, Johnston J, Tesin D, Davies M, Tam JM, Church GM, Walt DR.
J Am Chem Soc
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Engineering gene drive docking sites in a haplolethal locus in Anopheles gambiae.
Authors: Authors: Smidler AL, Marrogi EA, Scott S, Mameli E, Abernathy D, Akbari OS, Church GM, Catteruccia F, Esvelt K.
bioRxiv
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Circular Vectors as an efficient, fully synthetic, cell-free approach for preparing small circular DNA as a plasmid substitute for guide RNA expression in CRISPR-Cas9 genome editing.
Authors: Authors: Oliynyk RT, Church GM.
Nat Protoc
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Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues.
Authors: Authors: Stein J, Ericsson M, Nofal M, Magni L, Aufmkolk S, McMillan RB, Breimann L, Herlihy CP, Lee SD, Willemin A, Wohlmann J, Arguedas-Jimenez L, Yin P, Pombo A, Church GM, Wu CT.
bioRxiv
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Rapid human oogonia-like cell specification via transcription factor-directed differentiation.
Authors: Authors: Pierson Smela M, Kramme CC, Fortuna PRJ, Wolf B, Goel S, Adams J, Ma C, Velychko S, Widocki U, Srikar Kavirayuni V, Chen T, Vincoff S, Dong E, Kohman RE, Kobayashi M, Shioda T, Church GM, Chatterjee P.
EMBO Rep
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Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases.
Authors: Authors: Sundstrom J, Vanderleeden E, Barton NJ, Redick SD, Dawes P, Murray LF, Olson MN, Tran K, Chigas SM, Orszulak AR, Church GM, Readhead B, Oh HS, Harlan DM, Knipe DM, Wang JP, Chan Y, Lim ET.
Cells
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Cyanobacteria newly isolated from marine volcanic seeps display rapid sinking and robust, high-density growth.
Authors: Authors: Schubert MG, Tang T-C, Goodchild-Michelman IM, Ryon KA, Henriksen JR, Chavkin T, Wu Y, Miettinen TP, Van Wychen S, Dahlin LR, Spatafora D, Turco G, Guarnieri MT, Manalis SR, Kowitz J, Hann EC, Dhir R, Quatrini P, Mason CE, Church GM, Milazzo M, Tierney BT.
Appl Environ Microbiol
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Measurement of a-synuclein as protein cargo in plasma extracellular vesicles.
Authors: Authors: Gilboa T, Ter-Ovanesyan D, Wang SC, Whiteman S, Kannarkat GT, Church GM, Chen-Plotkin AS, Walt DR.
Proc Natl Acad Sci U S A
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