Steven McCarroll headshot

Steven A. McCarroll, Ph.D.

Dorothy and Milton Flier Professor of Biomedical Science and Genetics, Harvard Medical School
Director of Genomic Neurobiology, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard
617-432-7794
McCarroll Lab Website
Human and bacterial genetic variation shape oral microbiomes and health.
Authors: Authors: Kamitaki N, Handsaker RE, Hujoel MLA, Mukamel RE, Usher CL, McCarroll SA, Loh PR.
Nature
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Insights into DNA repeat expansions among 900,000 biobank participants.
Authors: Authors: Hujoel MLA, Handsaker RE, Tang D, Kamitaki N, Mukamel RE, Rubinacci S, Palamara PF, McCarroll SA, Loh PR.
Nature
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A supervised ontology-aware cell annotation method for single-cell transcriptomic data.
Authors: Authors: Magre N, Alshehri E, Grab F, Ordabayev Y, McCarroll SA, Babadi M, Fleming SJ.
bioRxiv
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A shared DNA-repeat toxicity threshold, reached somatically at cell-type-specific rates, unites cortical and striatal neurodegeneration in Huntington's disease.
Authors: Authors: Kashin S, Lee WS, McDonald TM, Morris K, Handsaker RE, Mello C, Spina L, Reed NM, de Rivera H, Jana SH, Hogan M, Berretta S, McCarroll SA.
bioRxiv
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Gene editing in "cell villages" enables exploring disease-relevant mutations in many genetic backgrounds.
Authors: Authors: Battaglia RA, Bolshakova S, Mazureac I, Liyanage D, Pettinari N, Johnson A, Crouse E, Habib S, Flessas I, Nadig A, Hawes D, Tegtmeyer M, Becker C, Ghosh S, Genovese G, Hogan M, Maglieri A, Barrett LE, Daheron L, McCarroll SA, Nehme R.
bioRxiv
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Genes and environment profoundly affect the human virome.
Authors: Authors: Kamitaki N, Tang D, McCarroll SA, Loh PR.
bioRxiv
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Higher dopamine D1 receptor expression in prefrontal parvalbumin neurons underlies higher distractibility in marmosets versus macaques.
Authors: Authors: Joyce MKP, Ivanov TG, Krienen FM, Mitchell JF, Ma S, Inoue W, Nandy AS, Datta D, Duque A, Arellano JI, Gupta R, Gonzalez-Burgos G, Lewis DA, Sestan N, McCarroll SA, Martinez-Trujillo J, Froudist-Walsh S, Arnsten AFT.
Commun Biol
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Human genetic variation shapes the response of neurons to interferons.
Authors: Authors: Andzelm MM, Bolshakova S, Pettinari N, Tegtmeyer M, Meyer D, Johnson A, Mello CJ, Yu CT, Mazureac I, Genovese G, Maglieri A, Ichihara K, Hogan M, Hawes D, McCarroll SA, Nehme R.
bioRxiv
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Transcriptome-wide analysis of differential expression in perturbation atlases.
Authors: Authors: Nadig A, Replogle JM, Pogson AN, Murthy M, McCarroll SA, Weissman JS, Robinson EB, O'Connor LJ.
Nat Genet
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Explainable modeling of single-cell perturbation data using attention and sparse dictionary learning.
Authors: Authors: Xu Y, Fleming S, Tegtmeyer M, McCarroll SA, Babadi M.
Cell Syst
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