Steven A. McCarroll

Steven A. McCarroll, Ph.D.

Dorothy and Milton Flier Professor of Biomedical Science and Genetics, Harvard Medical School

Director of Genomic Neurobiology, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard

617-432-7794

Publications

Long somatic DNA-repeat expansion drives neurodegeneration in Huntington's disease.

Authors: Authors: Handsaker RE, Kashin S, Reed NM, Tan S, Lee WS, McDonald TM, Morris K, Kamitaki N, Mullally CD, Morakabati NR, Goldman M, Lind G, Kohli R, Lawton E, Hogan M, Ichihara K, Berretta S, McCarroll SA.
Cell 2025-01-14
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Whole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia.

Authors: Authors: Li R, Taliun SAG, Liao K, Flickinger M, Sobell JL, Genovese G, Locke AE, Chiu RR, LeFaive J, Martins T, Chapman S, Neumann A, Handsaker RE, Arnett DK, Barnes KC, Boerwinkle E, Braff D, Cade BE, Fornage M, Gibbs RA, Hoth KF, Hou L, Kooperberg C, Loos RJF, Metcalf GA, Montgomery CG, Morrison AC, Qin ZS, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Viaud-Martinez KA, Bigdeli TB, Gabriel S, Zollner S, Smith AV, Abecasis G, McCarroll S, Pato MT, Pato CN, Boehnke M, Knowles J, Kang HM, Ophoff RA, Ernst J, Scott LJ.
medRxiv 2024-12-29
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Author Correction: Genetic drivers and cellular selection of female mosaic X chromosome loss.

Authors: Authors: Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat SM, Kentistou KA, Yang Z, Yu K, Vlasschaert C, Liu X, Brown DW, Hudjashov G, Gorman BR, Dennis J, Zhou W, Momozawa Y, Pyarajan S, Tuzov V, Pajuste FD, Aavikko M, Sipilä TP, Ghazal A, Huang WY, Freedman ND, Song L, Gardner EJ, Sankaran VG, Palotie A, Ollila HM, Tukiainen T, Chanock SJ, Mägi R, Natarajan P, Daly MJ, Bick A, McCarroll SA, Terao C, Loh PR, Ganna A, Perry JRB, Machiela MJ.
Nature 2024-12-03
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Insights into the causes and consequences of DNA repeat expansions from 700,000 biobank participants.

Authors: Authors: Hujoel MLA, Handsaker RE, Kamitaki N, Mukamel RE, Rubinacci S, Palamara PF, McCarroll SA, Loh PR.
bioRxiv 2024-11-26
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Calcium-permeable AMPA receptors govern PV neuron feature selectivity.

Authors: Authors: Hong I, Kim J, Hainmueller T, Kim DW, Keijser J, Johnson RC, Park SH, Limjunyawong N, Yang Z, Cheon D, Hwang T, Agarwal A, Cholvin T, Krienen FM, McCarroll SA, Dong X, Leopold DA, Blackshaw S, Sprekeler H, Bergles DE, Bartos M, Brown SP, Huganir RL.
Nature 2024-10-02
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A sequence of SVA retrotransposon insertions in ASIP shaped human pigmentation.

Authors: Authors: Kamitaki N, Hujoel MLA, Mukamel RE, Gebara E, McCarroll SA, Loh PR.
Nat Genet 2024-07-24
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Transcriptome-wide characterization of genetic perturbations.

Authors: Authors: Nadig A, Replogle JM, Pogson AN, McCarroll SA, Weissman JS, Robinson EB, O'Connor LJ.
bioRxiv 2024-07-03
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Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS.

Authors:
Nat Aging 2024-06-21
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Kynurenic acid inflammatory signaling expands in primates and impairs prefrontal cortical cognition.

Authors:
bioRxiv 2024-06-13
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Genetic drivers and cellular selection of female mosaic X chromosome loss.

Authors:
Nature 2024-06-12
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