Steven McCarroll headshot

Steven A. McCarroll, Ph.D.

Dorothy and Milton Flier Professor of Biomedical Science and Genetics, Harvard Medical School
Director of Genomic Neurobiology, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard
617-432-7794
McCarroll Lab Website
The DNA virome varies with human genes and environments.
Authors: Authors: Kamitaki N, Tang D, McCarroll SA, Loh PR.
Nature
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A multi-omic atlas in the African turquoise killifish reveals increased glucocorticoid signaling as a hallmark of brain aging.
Authors: Authors: Williams RG, Teefy BB, Lemus AJJ, Lee EH, Bhala R, Kim M, Zhou H, Adler A, Kashyap A, Cardenas GM, McCarroll SA, Tower J, Benayoun BA.
bioRxiv
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Inter-individual variation of cellular and gene-expression properties of the human striatum.
Authors: Authors: Burger S, Yoo O, Nemesh J, Muratoglu E, Vanderburg C, Yuan J, Shakir K, Mello CJ, Rayan NA, Milidantri J, Kim K, Drouin S, Finn E, Gao H, Budnik N, Goldman M, Fritch H, Genovese G, Hogan M, Catalini O, Kashin S, Rockweiler N, Wysoker A, Macaisa L, Reese L, Flowers K, Kraft AW, Fleming SJ, Coe M, Gunaratne R, Spina L, Crombie C, Mohsin A, Kamitaki N, Macosko EZ, Ichihara K, McCarroll SA.
bioRxiv
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Mesoscale molecular architecture of the human striatum across cell types and lifespan.
Authors: Authors: Kraft AW, Lee M, Rayan N, Gao H, Milidantri J, Vanderburg C, Balderrama K, Nadaf N, Kumar V, Flowers K, Finn E, Shabet M, Muratoglu E, Yoo O, Shakir K, Nemesh J, Burger S, Drouin S, Catalini O, Raj M, Mohsin A, Budnik N, Reese L, McCarroll SA, Ichihara K, Macosko EZ.
bioRxiv
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Human and bacterial genetic variation shape oral microbiomes and health.
Authors: Authors: Kamitaki N, Handsaker RE, Hujoel MLA, Mukamel RE, Usher CL, McCarroll SA, Loh PR.
Nature
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Insights into DNA repeat expansions among 900,000 biobank participants.
Authors: Authors: Hujoel MLA, Handsaker RE, Tang D, Kamitaki N, Mukamel RE, Rubinacci S, Palamara PF, McCarroll SA, Loh PR.
Nature
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Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness.
Authors: Authors: Yang S, Datta D, Krienen FM, Woo E, May A, Anderson GM, Galvin VC, Gonzalez-Burgos G, Lewis DA, Ling E, McCarroll SA, Arnsten AF, Wang M.
Mol Psychiatry
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Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia.
Authors: Authors: Li R, Gagliano Taliun SA, Liao K, Flickinger M, Sobell JL, Genovese G, Locke AE, Chiu RR, LeFaive J, Wang J, Martins T, Chapman S, Neumann A, Handsaker RE, Arnett DK, Barnes KC, Boerwinkle E, Braff D, Cade BE, Fornage M, Gibbs RA, Hoth KF, Hou L, Kooperberg C, Loos RJF, Metcalf GA, Montgomery CG, Morrison AC, Qin ZS, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Viaud-Martinez KA, Bigdeli TB, Gabriel S, Zollner S, Smith AV, Abecasis G, McCarroll SA, Pato MT, Pato CN, Boehnke M, Knowles J, Kang HM, Ophoff RA, Ernst J, Scott LJ.
HGG Adv
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A supervised ontology-aware cell annotation method for single-cell transcriptomic data.
Authors: Authors: Magre N, Alshehri E, Grab F, Ordabayev Y, McCarroll SA, Babadi M, Fleming SJ.
bioRxiv
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A shared DNA-repeat toxicity threshold, reached somatically at cell-type-specific rates, unites cortical and striatal neurodegeneration in Huntington's disease.
Authors: Authors: Kashin S, Lee WS, McDonald TM, Morris K, Handsaker RE, Mello C, Spina L, Reed NM, de Rivera H, Jana SH, Hogan M, Berretta S, McCarroll SA.
bioRxiv
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