Brian Seed headshot

Brian Seed, Ph.D.

Professor of Genetics
617-726-5975
Seed Lab Website
Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes.
Authors: Authors: Westerberg LS, Meelu P, Baptista M, Eston MA, Adamovich DA, Cotta-de-Almeida V, Seed B, Rosen MK, Vandenberghe P, Thrasher AJ, Klein C, Alt FW, Snapper SB.
J Exp Med
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Conformationally constrained spiro C-arylglucosides as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
Authors: Authors: Lv B, Feng Y, Dong J, Xu M, Xu B, Zhang W, Sheng Z, Welihinda A, Seed B, Chen Y.
ChemMedChem
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Fluorosomes: a convenient new reagent to detect and block multivalent and complex receptor-ligand interactions.
Authors: Authors: Kueng HJ, Manta C, Haiderer D, Leb VM, Schmetterer KG, Neunkirchner A, Byrne RA, Scheinecker C, Steinberger P, Seed B, Pickl WF.
FASEB J
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PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification.
Authors: Authors: Spandidos A, Wang X, Wang H, Seed B.
Nucleic Acids Res
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Exploration of O-spiroketal C-arylglucosides as novel and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
Authors: Authors: Lv B, Xu B, Feng Y, Peng K, Xu G, Du J, Zhang L, Zhang W, Zhang T, Zhu L, Ding H, Sheng Z, Welihinda A, Seed B, Chen Y.
Bioorg Med Chem Lett
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O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
Authors: Authors: Xu B, Lv B, Feng Y, Xu G, Du J, Welihinda A, Sheng Z, Seed B, Chen Y.
Bioorg Med Chem Lett
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Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules.
Authors: Authors: Leb VM, Jahn-Schmid B, Kueng HJ, Schmetterer KG, Haiderer D, Neunkirchner A, Fischer GF, Hartl A, Thalhamer J, Steinberger P, Bohle B, Seed B, Pickl WF.
J Allergy Clin Immunol
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Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress.
Authors: Authors: Adams JC, Seed B, Lu N, Landry A, Xavier RJ.
Neuroscience
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Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.
Authors: Authors: Luong MX, Tam J, Lin Q, Hagendoorn J, Moore KJ, Padera TP, Seed B, Fukumura D, Kucherlapati R, Jain RK.
J Cell Physiol
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A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance.
Authors: Authors: Spandidos A, Wang X, Wang H, Dragnev S, Thurber T, Seed B.
BMC Genomics
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