Brian Seed, Ph.D.
Professor of Genetics, Harvard Medical School
Principal Investigator, Center for Computational and Integrative Biology, Massachusetts General Hospital
Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice.
Authors: Authors: Beck PL, Xavier R, Lu N, Nanda NN, Dinauer M, Podolsky DK, Seed B.
Gastroenterology
View full abstract on Pubmed
Gastroenterology
View full abstract on Pubmed
Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.
The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation.
Authors: Authors: Izumi KM, Cahir McFarland ED, Ting AT, Riley EA, Seed B, Kieff ED.
Mol Cell Biol
View full abstract on Pubmed
Mol Cell Biol
View full abstract on Pubmed
Membrane compartmentation and the response to antigen.
Tumor induction of VEGF promoter activity in stromal cells.
Authors: Authors: Fukumura D, Xavier R, Sugiura T, Chen Y, Park EC, Lu N, Selig M, Nielsen G, Taksir T, Jain RK, Seed B.
Cell
View full abstract on Pubmed
Cell
View full abstract on Pubmed
Muskelin, a novel intracellular mediator of cell adhesive and cytoskeletal responses to thrombospondin-1.
PPARgamma and colorectal carcinoma: conflicts in a nuclear family.
Membrane compartmentation is required for efficient T cell activation.
Authors: Authors: Xavier R, Brennan T, Li Q, McCormack C, Seed B.
Immunity
View full abstract on Pubmed
Immunity
View full abstract on Pubmed
Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage.
Authors: Authors: André S, Seed B, Eberle J, Schraut W, Bültmann A, Haas J.
J Virol
View full abstract on Pubmed
J Virol
View full abstract on Pubmed
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines.