beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation.
Authors: Authors: Liu C, Kato Y, Zhang Z, Do VM, Yankner BA, He X.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis.
Authors: Authors: Zhang Z, Hartmann H, Do VM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Sommer B, van de Wetering M, Clevers H, Saftig P, De Strooper B, He X, Yankner BA.
Nature
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Nature
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Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity.
Authors: Authors: Geula C, Wu CK, Saroff D, Lorenzo A, Yuan M, Yankner BA.
Nat Med
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Nat Med
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Monster plaques: what they tell us about Alzheimer's disease.
Neuronal localization of presenilin-1 and association with amyloid plaques and neurofibrillary tangles in Alzheimer's disease.
Authors: Authors: Busciglio J, Hartmann H, Lorenzo A, Wong C, Baumann K, Sommer B, Staufenbiel M, Yankner BA.
J Neurosci
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J Neurosci
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Developmental regulation of presenilin-1 processing in the brain suggests a role in neuronal differentiation.
Authors: Authors: Hartmann H, Busciglio J, Baumann KH, Staufenbiel M, Yankner BA.
J Biol Chem
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J Biol Chem
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Distinct processing of endogenous and overexpressed recombinant presenilin 1.
Authors: Authors: Baumann K, Paganetti PA, Sturchler-Pierrat C, Wong C, Hartmann H, Cescato R, Frey P, Yankner BA, Sommer B, Staufenbiel M.
Neurobiol Aging
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Neurobiol Aging
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New clues to Alzheimer's disease: unraveling the roles of amyloid and tau.
Mechanisms of neuronal degeneration in Alzheimer's disease.
Amyloid fibril toxicity in Alzheimer's disease and diabetes.