Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.
Intracellular accumulation of beta-amyloid in cells expressing the Swedish mutant amyloid precursor protein.
Authors: Authors: Martin BL, Schrader-Fischer G, Busciglio J, Duke M, Paganetti P, Yankner BA.
J Biol Chem
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J Biol Chem
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beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.
Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative.
Authors: Authors: Gabuzda D, Busciglio J, Chen LB, Matsudaira P, Yankner BA.
J Biol Chem
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J Biol Chem
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Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus.
Inhibition of beta-amyloid production by activation of protein kinase C.
beta-Amyloid neurotoxicity in human cortical culture is not mediated by excitotoxins.
Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells.
Authors: Authors: Busciglio J, Gabuzda DH, Matsudaira P, Yankner BA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Secretogranin I/chromogranin B is a heparin-binding adhesive protein.