Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system.
Authors: Authors: Lee PC, Dodart JC, Aron L, Finley LW, Bronson RT, Haigis MC, Yankner BA, Harper JW.
Mol Cell
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Mol Cell
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Sustained axon regeneration induced by co-deletion of PTEN and SOCS3.
Authors: Authors: Sun F, Park KK, Belin S, Wang D, Lu T, Chen G, Zhang K, Yeung C, Feng G, Yankner BA, He Z.
Nature
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Nature
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The aging stress response.
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.
Authors: Authors: Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Negative regulation of Vps34 by Cdk mediated phosphorylation.
Authors: Authors: Furuya T, Kim M, Lipinski M, Li J, Kim D, Lu T, Shen Y, Rameh L, Yankner B, Tsai LH, Yuan J.
Mol Cell
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Mol Cell
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Neural mechanisms of ageing and cognitive decline.
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging.
Authors: Authors: Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA.
Cell
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Cell
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Evolution of the aging brain transcriptome and synaptic regulation.
Authors: Authors: Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA.
PLoS One
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PLoS One
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Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Authors: Authors: Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE.
Nat Neurosci
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Nat Neurosci
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