Bruce Yankner headshot

Bruce A. Yankner, M.D., Ph.D.

Professor of Genetics
The aging stress response.
Authors: Authors: Haigis MC, Yankner BA.
Mol Cell
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Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.
Authors: Authors: Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J.
Proc Natl Acad Sci U S A
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Negative regulation of Vps34 by Cdk mediated phosphorylation.
Authors: Authors: Furuya T, Kim M, Lipinski M, Li J, Kim D, Lu T, Shen Y, Rameh L, Yankner B, Tsai LH, Yuan J.
Mol Cell
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Neural mechanisms of ageing and cognitive decline.
Authors: Authors: Bishop NA, Lu T, Yankner BA.
Nature
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Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
Authors: Authors: Yankner BA, Lu T.
J Biol Chem
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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging.
Authors: Authors: Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA.
Cell
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Evolution of the aging brain transcriptome and synaptic regulation.
Authors: Authors: Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA.
PLoS One
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Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Authors: Authors: Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE.
Nat Neurosci
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The aging brain.
Authors: Authors: Yankner BA, Lu T, Loerch P.
Annu Rev Pathol
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Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium.
Authors: Authors: Isaacs AM, Senn DB, Yuan M, Shine JP, Yankner BA.
J Biol Chem
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