Constance Cepko

Constance Cepko, Ph.D.

Bullard Professor of Genetics and Neuroscience, Harvard Medical School

Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary

Investigator, Howard Hughes Medical Institute

617-432-7618

Cepko Lab Website

Publications

Combined Disruption of Multiple Cytokine Signaling Pathways Enables One-Step Anterograde Tracing with Vesicular Stomatitis Virus.

Authors: Authors: Ma X, Cepko CL.
J Neurosci 2026-09-30
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Host Endoplasmic Reticulum Stress and Interferon Responses Contribute to AAV-Induced Ocular Toxicity.

Authors: Authors: Gardner A, Hong C, Zhao SR, Daniels A, Cepko CL.
bioRxiv 2026-09-23
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AAV-NRF2 protects retinal and choroidal vasculature in a GDF15-dependent manner in an oxidative damage model of AMD.

Authors: Authors: Wang S, Zhao S, Daniels A, Naaman E, Gardner A, Smith LEH, Cepko CL.
Proc Natl Acad Sci U S A 2026-08-18
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Distinct neurogenic progenitor cell populations balance cell type production in the embryonic mouse retina.

Authors: Authors: Bushnell HL, Cepko CL.
bioRxiv 2026-08-04
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Neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD Alzheimer's disease model mice.

Authors: Authors: Sadleir KR, Gomez KP, Chandra S, Ley ML, Khatri AW, Guo J, Xue Y, Cepko CL, Vassar R.
Alzheimers Res Ther 2026-06-03
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AAV NRF2 gene therapy preserves retinal structure and function in rodent models of oxidative damage.

Authors: Authors: Gardner A, Wang S, Daniels A, Li D, Wu C, Lin L, Hong C, Zhao SR, Born RT, Kruczek K, Weist G, Real LB, Wicks J, Nayal M, Carter A, Ott C, Haurigot V, Cepko CL.
Mol Ther 2026-06-03
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AAV NRF2 gene therapy preserves retinal structure and function in rodent models of oxidative damage.

Authors: Authors: Gardner A, Wang S, Daniels A, Li D, Wu C, Lin L, Hong C, Zhao SR, Born RT, Kruczek K, Weist G, Barrio Real L, Wicks J, Nayal M, Carter A, Ott C, Haurigot V, Cepko CL.
Mol Ther 2026-06-03
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Tbx genes influence early gene expression and photoreceptor patterning in the chick retina.

Authors: Authors: Ayten M, Joisher HNV, Prabhakara C, Cepko C.
Dev Biol 2026-05-01
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Humanized extracellular vesicles for efficient RNA delivery.

Authors: Authors: Ma X, Zhao SR, Cepko CL.
Proc Natl Acad Sci U S A 2026-04-14
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Neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD Alzheimer's disease model mice.

Authors: Authors: Sadleir KR, Gomez KP, Chandra S, Ley ML, Khatri AW, Guo J, Xue Y, Cepko CL, Vassar R.
bioRxiv 2026-03-18
View full abstract on Pubmed