Constance Cepko, Ph.D.
Bullard Professor of Genetics and Neuroscience, Harvard Medical School
Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Investigator, Howard Hughes Medical Institute
Retinoic acid regulates the expression of dorsoventral topographic guidance molecules in the chick retina.
A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.
A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells.
The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina.
The rod photoreceptor pattern is set at the optic vesicle stage and requires spatially restricted cVax expression.
Synaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant mice.
Authors: Authors: Morrow EM, Furukawa T, Raviola E, Cepko CL.
BMC Neurosci
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BMC Neurosci
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Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression.
Authors: Authors: Kim JS, Coon SL, Blackshaw S, Cepko CL, Møller M, Mukda S, Zhao WQ, Charlton CG, Klein DC.
J Biol Chem
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J Biol Chem
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Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10.
Authors: Authors: Rowan S, Chen CM, Young TL, Fisher DE, Cepko CL.
Development
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Development
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Genomic analysis of mouse retinal development.
Authors: Authors: Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL.
PLoS Biol
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PLoS Biol
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Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter.