Constance Cepko, Ph.D.
Bullard Professor of Genetics and Neuroscience, Harvard Medical School
Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Investigator, Howard Hughes Medical Institute
Retinal gene therapy coming of age.
Pseudotyped retroviruses for infecting axolotl in vivo and in vitro.
Authors: Authors: Whited JL, Tsai SL, Beier KT, White JN, Piekarski N, Hanken J, Cepko CL, Tabin CJ.
Development
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Development
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Transsynaptic tracing with vesicular stomatitis virus reveals novel retinal circuitry.
Authors: Authors: Beier KT, Borghuis BG, El-Danaf RN, Huberman AD, Demb JB, Cepko CL.
J Neurosci
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J Neurosci
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Vesicular stomatitis virus with the rabies virus glycoprotein directs retrograde transsynaptic transport among neurons in vivo.
Authors: Authors: Beier KT, Saunders AB, Oldenburg IA, Sabatini BL, Cepko CL.
Front Neural Circuits
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Front Neural Circuits
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Lineage analysis of the late otocyst stage mouse inner ear by transuterine microinjection of a retroviral vector encoding alkaline phosphatase and an oligonucleotide library.
Authors: Authors: Jiang H, Wang L, Beier KT, Cepko CL, Fekete DM, Brigande JV.
PLoS One
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PLoS One
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Viral tracing of genetically defined neural circuitry.
Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates.
Authors: Authors: Hafler BP, Surzenko N, Beier KT, Punzo C, Trimarchi JM, Kong JH, Cepko CL.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Emerging gene therapies for retinal degenerations.
Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame?
Gene expression changes within Müller glial cells in retinitis pigmentosa.