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David Andrew Sinclair, Ph.D.

Professor of Genetics
Yeast aging research: recent advances and medical relevance.
Authors: Authors: Sinclair DA.
Cell Mol Life Sci
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Passage through stationary phase advances replicative aging in Saccharomyces cerevisiae.
Authors: Authors: Ashrafi K, Sinclair D, Gordon JI, Guarente L.
Proc Natl Acad Sci U S A
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The Additional sex combs gene of Drosophila is required for activation and repression of homeotic loci, and interacts specifically with Polycomb and super sex combs.
Authors: Authors: Milne TA, Sinclair DA, Brock HW.
Mol Gen Genet
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MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks.
Authors: Authors: Mills KD, Sinclair DA, Guarente L.
Cell
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Control of expression of one-carbon metabolism genes of Saccharomyces cerevisiae is mediated by a tetrahydrofolate-responsive protein binding to a glycine regulatory region including a core 5'-CTTCTT-3' motif.
Authors: Authors: Hong SP, Piper MD, Sinclair DA, Dawes IW.
J Biol Chem
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Genomic imprinting and position-effect variegation in Drosophila melanogaster.
Authors: Authors: Lloyd VK, Sinclair DA, Grigliatti TA.
Genetics
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Molecular biology of aging.
Authors: Authors: Johnson FB, Sinclair DA, Guarente L.
Cell
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Emergency department observation unit: can it be funded through reduced inpatient admission?
Authors: Authors: Sinclair D, Green R.
Ann Emerg Med
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The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals.
Authors: Authors: Stankunas K, Berger J, Ruse C, Sinclair DA, Randazzo F, Brock HW.
Development
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Suppressors of position-effect variegation in Drosophila melanogaster affect expression of the heterochromatic gene light in the absence of a chromosome rearrangement.
Authors: Authors: Clegg NJ, Honda BM, Whitehead IP, Grigliatti TA, Wakimoto B, Brock HW, Lloyd VK, Sinclair DA.
Genome
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