The Ausubel laboratory uses genetic, genomic, and chemical genetic approaches to: (1) elucidate the molecular basis of microbial pathogenesis in the bacterial pathogens Pseudomonas aeruginosa and Pseudomonas syringae and (2) identify the components of the signaling pathways involved in the host innate immune response in the plant Arabidopsis thaliana and the nematode Caenorhabditis elegans.
Genome-wide mapping with biallelic markers in Arabidopsis thaliana.
Authors: Authors: Cho RJ, Mindrinos M, Richards DR, Sapolsky RJ, Anderson M, Drenkard E, Dewdney J, Reuber TL, Stammers M, Federspiel N, Theologis A, Yang WH, Hubbell E, Au M, Chung EY, Lashkari D, Lemieux B, Dean C, Lipshutz RJ, Ausubel FM, Davis RW, Oefner PJ.
Nat Genet
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Nat Genet
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Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors.
Authors: Authors: Tan MW, Rahme LG, Sternberg JA, Tompkins RG, Ausubel FM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis.
Authors: Authors: Tan MW, Mahajan-Miklos S, Ausubel FM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model.
Modulation of expression of the ToxR regulon in Vibrio cholerae by a member of the two-component family of response regulators.
Authors: Authors: Wong SM, Carroll PA, Rahme LG, Ausubel FM, Calderwood SB.
Infect Immun
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Infect Immun
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Correlation of defense gene induction defects with powdery mildew susceptibility in Arabidopsis enhanced disease susceptibility mutants.
Authors: Authors: Reuber TL, Plotnikova JM, Dewdney J, Rogers EE, Wood W, Ausubel FM.
Plant J
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Plant J
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Isolation of new Arabidopsis mutants with enhanced disease susceptibility to Pseudomonas syringae by direct screening.
A light-independent developmental mechanism potentiates flavonoid gene expression in Arabidopsis seedlings.
Use of cleaved amplified polymorphic sequences (CAPS) as genetic markers in Arabidopsis thaliana.
Authors: Authors: Glazebrook J, Drenkard E, Preuss D, Ausubel FM.
Methods Mol Biol
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Methods Mol Biol
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The epidemiology of resistance to ofloxacin and oxacillin among clinical coagulase-negative staphylococcal isolates: analysis of risk factors and strain types.
Authors: Authors: Pegues DA, Colby C, Hibberd PL, Cohen LG, Ausubel FM, Calderwood SB, Hooper DC.
Clin Infect Dis
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Clin Infect Dis
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