The Ausubel laboratory uses genetic, genomic, and chemical genetic approaches to: (1) elucidate the molecular basis of microbial pathogenesis in the bacterial pathogens Pseudomonas aeruginosa and Pseudomonas syringae and (2) identify the components of the signaling pathways involved in the host innate immune response in the plant Arabidopsis thaliana and the nematode Caenorhabditis elegans.
Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis.
Authors: Authors: Shirley BW, Kubasek WL, Storz G, Bruggemann E, Koornneef M, Ausubel FM, Goodman HM.
Plant J
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Plant J
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Common virulence factors for bacterial pathogenicity in plants and animals.
Authors: Authors: Rahme LG, Stevens EJ, Wolfort SF, Shao J, Tompkins RG, Ausubel FM.
Science
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Science
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Use of Arabidopsis thaliana defense-related mutants to dissect the plant response to pathogens.
Authors: Authors: Ausubel FM, Katagiri F, Mindrinos M, Glazebrook J.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Molecular genetics of plant disease resistance.
Authors: Authors: Staskawicz BJ, Ausubel FM, Baker BJ, Ellis JG, Jones JD.
Science
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Science
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Differential mRNA display.
Haplotypic divergence coupled with lack of diversity at the Arabidopsis thaliana alcohol dehydrogenase locus: roles for both balancing and directional selection?
Authors: Authors: Hanfstingl U, Berry A, Kellogg EA, Costa JT, Rüdiger W, Ausubel FM.
Genetics
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Genetics
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The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats.
Isolation of phytoalexin-deficient mutants of Arabidopsis thaliana and characterization of their interactions with bacterial pathogens.
Programmed cell death in plants: a pathogen-triggered response activated coordinately with multiple defense functions.
Signal transduction mutants of Arabidopsis uncouple nuclear CAB and RBCS gene expression from chloroplast development.