The Ausubel laboratory uses genetic, genomic, and chemical genetic approaches to: (1) elucidate the molecular basis of microbial pathogenesis in the bacterial pathogens Pseudomonas aeruginosa and Pseudomonas syringae and (2) identify the components of the signaling pathways involved in the host innate immune response in the plant Arabidopsis thaliana and the nematode Caenorhabditis elegans.
Insect-derived cecropins display activity against Acinetobacter baumannii in a whole-animal high-throughput Caenorhabditis elegans model.
Authors: Authors: Jayamani E, Rajamuthiah R, Larkins-Ford J, Fuchs BB, Conery AL, Vilcinskas A, Ausubel FM, Mylonakis E.
Antimicrob Agents Chemother
View full abstract on Pubmed
Antimicrob Agents Chemother
View full abstract on Pubmed
Associations with rhizosphere bacteria can confer an adaptive advantage to plants.
Jasmonate signalling in Arabidopsis involves SGT1b-HSP70-HSP90 chaperone complexes.
Authors: Authors: Zhang XC, Millet YA, Cheng Z, Bush J, Ausubel FM.
Nat Plants
View full abstract on Pubmed
Nat Plants
View full abstract on Pubmed
On the Mechanism of Berberine-INF55 (5-Nitro-2-phenylindole) Hybrid Antibacterials.
Authors: Authors: Dolla NK, Chen C, Larkins-Ford J, Rajamuthiah R, Jagadeesan S, Conery AL, Ausubel FM, Mylonakis E, Bremner JB, Lewis K, Kelso MJ.
Aust J Chem
View full abstract on Pubmed
Aust J Chem
View full abstract on Pubmed
Repurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureus.
Authors: Authors: Rajamuthiah R, Fuchs BB, Conery AL, Kim W, Jayamani E, Kwon B, Ausubel FM, Mylonakis E.
PLoS One
View full abstract on Pubmed
PLoS One
View full abstract on Pubmed
A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus.
Authors: Authors: Rajamuthiah R, Jayamani E, Conery AL, Fuchs BB, Kim W, Johnston T, Vilcinskas A, Ausubel FM, Mylonakis E.
PLoS One
View full abstract on Pubmed
PLoS One
View full abstract on Pubmed
Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy.
Authors: Authors: Kim W, Conery AL, Rajamuthiah R, Fuchs BB, Ausubel FM, Mylonakis E.
PLoS One
View full abstract on Pubmed
PLoS One
View full abstract on Pubmed
Associations with rhizosphere bacteria can confer an adaptive advantage to plants.
Next-Gen Sequencing-Based Mapping and Identification of Ethyl Methanesulfonate-Induced Mutations in Arabidopsis thaliana.
Authors: Authors: Zhang XC, Millet Y, Ausubel FM, Borowsky M.
Curr Protoc Mol Biol
View full abstract on Pubmed
Curr Protoc Mol Biol
View full abstract on Pubmed
Twists and turns: my career path and concerns about the future.