The Ausubel laboratory uses genetic, genomic, and chemical genetic approaches to: (1) elucidate the molecular basis of microbial pathogenesis in the bacterial pathogens Pseudomonas aeruginosa and Pseudomonas syringae and (2) identify the components of the signaling pathways involved in the host innate immune response in the plant Arabidopsis thaliana and the nematode Caenorhabditis elegans.
"First generation" automated DNA sequencing technology.
Authors: Authors: Slatko BE, Kieleczawa J, Ju J, Gardner AF, Hendrickson CL, Ausubel FM.
Curr Protoc Mol Biol
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Curr Protoc Mol Biol
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UV-C-irradiated Arabidopsis and tobacco emit volatiles that trigger genomic instability in neighboring plants.
Authors: Authors: Yao Y, Danna CH, Zemp FJ, Titov V, Ciftci ON, Przybylski R, Ausubel FM, Kovalchuk I.
Plant Cell
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Plant Cell
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Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses.
Authors: Authors: Pukkila-Worley R, Ausubel FM, Mylonakis E.
PLoS Pathog
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PLoS Pathog
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The Arabidopsis flagellin receptor FLS2 mediates the perception of Xanthomonas Ax21 secreted peptides.
Authors: Authors: Danna CH, Millet YA, Koller T, Han SW, Bent AF, Ronald PC, Ausubel FM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Retraction. Mediation of pathogen resistance by exudation of antimicrobials from roots.
Mining the plant-herbivore interface with a leafmining Drosophila of Arabidopsis.
Authors: Authors: Whiteman NK, Groen SC, Chevasco D, Bear A, Beckwith N, Gregory TR, Denoux C, Mammarella N, Ausubel FM, Pierce NE.
Mol Ecol
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Mol Ecol
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A high throughput amenable Arabidopsis-P. aeruginosa system reveals a rewired regulatory module and the utility to identify potent anti-infectives.
Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components.
Authors: Authors: Tomkiewicz D, Casadei G, Larkins-Ford J, Moy TI, Garner J, Bremner JB, Ausubel FM, Lewis K, Kelso MJ.
Antimicrob Agents Chemother
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Antimicrob Agents Chemother
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Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus.
Authors: Authors: Irazoqui JE, Troemel ER, Feinbaum RL, Luhachack LG, Cezairliyan BO, Ausubel FM.
PLoS Pathog
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PLoS Pathog
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RESOLVING CLUSTERED WORMS VIA PROBABILISTIC SHAPE MODELS.
Authors: Authors: Wählby C, Riklin-Raviv T, Ljosa V, Conery AL, Golland P, Ausubel FM, Carpenter AE.
Proc IEEE Int Symp Biomed Imaging
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Proc IEEE Int Symp Biomed Imaging
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