Gary B. Ruvkun, Ph.D.
Professor of Genetics, Harvard Medical School
Department of Molecular Biology, Massachusetts General Hospital
Graded expression of ceh-14 reporters in the hypodermis is induced by a gonadal signal.
Authors: Authors: Kagoshima H, Sommer R, Reinhart BJ, Cassata G, Ruvkun G, Bürglin TR.
Dev Genes Evol
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Dev Genes Evol
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Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells.
Authors: Authors: Nasrin N, Ogg S, Cahill CM, Biggs W, Nui S, Dore J, Calvo D, Shi Y, Ruvkun G, Alexander-Bridges MC.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor.
Authors: Authors: Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G.
Mol Cell
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Mol Cell
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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans.
Authors: Authors: Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, Horvitz HR, Ruvkun G.
Nature
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Nature
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Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant.
A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum.
Authors: Authors: Tissenbaum HA, Hawdon J, Perregaux M, Hotez P, Guarente L, Ruvkun G.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Themes from a NASA workshop on gene regulatory processes in development and evolution.
Alternative olfactory neuron fates are specified by the LIM homeobox gene lim-4.
Authors: Authors: Sagasti A, Hobert O, Troemel ER, Ruvkun G, Bargmann CI.
Genes Dev
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Genes Dev
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A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans.
Authors: Authors: Paradis S, Ailion M, Toker A, Thomas JH, Ruvkun G.
Genes Dev
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Genes Dev
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