Gary B. Ruvkun, Ph.D.
Professor of Genetics, Harvard Medical School
Department of Molecular Biology, Massachusetts General Hospital
An image analysis toolbox for high-throughput C. elegans assays.
Authors: Authors: Wählby C, Kamentsky L, Liu ZH, Riklin-Raviv T, Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O, Ljosa V, Irazoqui JE, Golland P, Ruvkun G, Ausubel FM, Carpenter AE.
Nat Methods
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Nat Methods
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Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses.
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans.
PIWI associated siRNAs and piRNAs specifically require the Caenorhabditis elegans HEN1 ortholog henn-1.
Authors: Authors: Montgomery TA, Rim YS, Zhang C, Dowen RH, Phillips CM, Fischer SE, Ruvkun G.
PLoS Genet
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PLoS Genet
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Prediction of C. elegans longevity genes by human and worm longevity networks.
Authors: Authors: Tacutu R, Shore DE, Budovsky A, de Magalhães JP, Ruvkun G, Fraifeld VE, Curran SP.
PLoS One
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PLoS One
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Repression of germline RNAi pathways in somatic cells by retinoblastoma pathway chromatin complexes.
Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways.
Regulation of the C. elegans molt by pqn-47.
The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.
Authors: Authors: Fischer SE, Montgomery TA, Zhang C, Fahlgren N, Breen PC, Hwang A, Sullivan CM, Carrington JC, Ruvkun G.
PLoS Genet
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PLoS Genet
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The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA.