Gary B. Ruvkun

Gary B. Ruvkun, Ph.D.

Professor of Genetics, Harvard Medical School

Department of Molecular Biology, Massachusetts General Hospital

617-726-5959

Ruvkun Lab Website

Publications

New insights into siRNA amplification and RNAi.

Authors: Authors: Zhang C, Ruvkun G.
RNA Biol 2012-08-01
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MUT-16 promotes formation of perinuclear mutator foci required for RNA silencing in the C. elegans germline.

Authors: Authors: Phillips CM, Montgomery TA, Breen PC, Ruvkun G.
Genes Dev 2012-07-01
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The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification.

Authors: Authors: Zhang C, Montgomery TA, Fischer SE, Garcia SM, Riedel CG, Fahlgren N, Sullivan CM, Carrington JC, Ruvkun G.
Curr Biol 2012-05-22
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An image analysis toolbox for high-throughput C. elegans assays.

Authors: Authors: Wählby C, Kamentsky L, Liu ZH, Riklin-Raviv T, Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O, Ljosa V, Irazoqui JE, Golland P, Ruvkun G, Ausubel FM, Carpenter AE.
Nat Methods 2012-04-22
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Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses.

Authors: Authors: Melo JA, Ruvkun G.
Cell 2012-04-13
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The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans.

Authors: Authors: Shi Z, Ruvkun G.
Proc Natl Acad Sci U S A 2012-03-20
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PIWI associated siRNAs and piRNAs specifically require the Caenorhabditis elegans HEN1 ortholog henn-1.

Authors: Authors: Montgomery TA, Rim YS, Zhang C, Dowen RH, Phillips CM, Fischer SE, Ruvkun G.
PLoS Genet 2012-01-01
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Prediction of C. elegans longevity genes by human and worm longevity networks.

Authors: Authors: Tacutu R, Shore DE, Budovsky A, de Magalhães JP, Ruvkun G, Fraifeld VE, Curran SP.
PLoS One 2012-01-01
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Repression of germline RNAi pathways in somatic cells by retinoblastoma pathway chromatin complexes.

Authors: Authors: Wu X, Shi Z, Cui M, Han M, Ruvkun G.
PLoS Genet 2012-01-01
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Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways.

Authors: Authors: Shore DE, Carr CE, Ruvkun G.
PLoS Genet 2012-01-01
View full abstract on Pubmed