
Gary B. Ruvkun, Ph.D.
Professor of Genetics, Harvard Medical School
Department of Molecular Biology, Massachusetts General Hospital
Regulation of the C. elegans molt by pqn-47.
The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.
Authors: Authors: Fischer SE, Montgomery TA, Zhang C, Fahlgren N, Breen PC, Hwang A, Sullivan CM, Carrington JC, Ruvkun G.
PLoS Genet
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PLoS Genet
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The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA.
RNAi screening for fat regulatory genes with SRS microscopy.
Authors: Authors: Wang MC, Min W, Freudiger CW, Ruvkun G, Xie XS.
Nat Methods
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Nat Methods
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mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans.
Authors: Authors: Zhang C, Montgomery TA, Gabel HW, Fischer SE, Phillips CM, Fahlgren N, Sullivan CM, Carrington JC, Ruvkun G.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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The C. elegans DAF-2 insulin-like receptor is abundantly expressed in the nervous system and regulated by nutritional status.
Authors: Authors: Kimura KD, Riddle DL, Ruvkun G.
Cold Spring Harb Symp Quant Biol
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Cold Spring Harb Symp Quant Biol
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Cancer. Germ cell genes and cancer.
MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.
RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.
Authors: Authors: Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT.
PLoS One
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PLoS One
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C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.
Authors: Authors: O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G.
Cell Metab
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Cell Metab
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