Gary Ruvkun headshot

Gary B. Ruvkun, Ph.D.

Professor of Genetics, Harvard Medical School
Department of Molecular Biology, Massachusetts General Hospital
RNAi screening for fat regulatory genes with SRS microscopy.
Authors: Authors: Wang MC, Min W, Freudiger CW, Ruvkun G, Xie XS.
Nat Methods
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mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans.
Authors: Authors: Zhang C, Montgomery TA, Gabel HW, Fischer SE, Phillips CM, Fahlgren N, Sullivan CM, Carrington JC, Ruvkun G.
Proc Natl Acad Sci U S A
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The C. elegans DAF-2 insulin-like receptor is abundantly expressed in the nervous system and regulated by nutritional status.
Authors: Authors: Kimura KD, Riddle DL, Ruvkun G.
Cold Spring Harb Symp Quant Biol
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Cancer. Germ cell genes and cancer.
Authors: Authors: Wu X, Ruvkun G.
Science
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MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.
Authors: Authors: Meli VS, Osuna B, Ruvkun G, Frand AR.
Mol Biol Cell
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RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.
Authors: Authors: Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT.
PLoS One
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C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.
Authors: Authors: O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G.
Cell Metab
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A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.
Authors: Authors: Curran SP, Wu X, Riedel CG, Ruvkun G.
Nature
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Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans.
Authors: Authors: Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G.
Genes Dev
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Biosynthesis of the Caenorhabditis elegans dauer pheromone.
Authors: Authors: Butcher RA, Ragains JR, Li W, Ruvkun G, Clardy J, Mak HY.
Proc Natl Acad Sci U S A
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