Gary Ruvkun headshot

Gary B. Ruvkun, Ph.D.

Professor of Genetics, Harvard Medical School
Department of Molecular Biology, Massachusetts General Hospital
Regulation of the C. elegans molt by pqn-47.
Authors: Authors: Russel S, Frand AR, Ruvkun G.
Dev Biol
View full abstract on Pubmed
The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.
Authors: Authors: Fischer SE, Montgomery TA, Zhang C, Fahlgren N, Breen PC, Hwang A, Sullivan CM, Carrington JC, Ruvkun G.
PLoS Genet
View full abstract on Pubmed
The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA.
Authors: Authors: Hayes GD, Riedel CG, Ruvkun G.
Genes Dev
View full abstract on Pubmed
RNAi screening for fat regulatory genes with SRS microscopy.
Authors: Authors: Wang MC, Min W, Freudiger CW, Ruvkun G, Xie XS.
Nat Methods
View full abstract on Pubmed
mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans.
Authors: Authors: Zhang C, Montgomery TA, Gabel HW, Fischer SE, Phillips CM, Fahlgren N, Sullivan CM, Carrington JC, Ruvkun G.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
The C. elegans DAF-2 insulin-like receptor is abundantly expressed in the nervous system and regulated by nutritional status.
Authors: Authors: Kimura KD, Riddle DL, Ruvkun G.
Cold Spring Harb Symp Quant Biol
View full abstract on Pubmed
Cancer. Germ cell genes and cancer.
Authors: Authors: Wu X, Ruvkun G.
Science
View full abstract on Pubmed
MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.
Authors: Authors: Meli VS, Osuna B, Ruvkun G, Frand AR.
Mol Biol Cell
View full abstract on Pubmed
RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.
Authors: Authors: Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT.
PLoS One
View full abstract on Pubmed
C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.
Authors: Authors: O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G.
Cell Metab
View full abstract on Pubmed