A Simple, Ultrastable, and Cost-Effective Oxygen-Scavenging System for Long-Term DNA-PAINT Imaging.
Engineered base editors with reduced bystander editing through directed evolution.
Authors: Authors: Perrotta RM, Vinke S, Ferreira R, Moret M, Mahas A, Chiappino-Pepe A, Riedmayr LM, Mehra AT, Lehmann LS, Church GM.
Nat Biotechnol
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Nat Biotechnol
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Plasmid2MC: efficient cell-free generation of high-purity minicircle DNA for genome editing in mammalian cells.
Authors: Authors: Oliynyk RT, Mahas A, Karpinski E, Church GM.
Commun Biol
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Commun Biol
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Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets.
Authors: Authors: Plummer JT, Dezem FS, Cook DP, Park J, Zhang L, Liu Y, Marção M, DuBose H, Wani A, Wise K, Roach M, Harvey K, Wang T, Jensen KB, Morosini N, De Gregorio R, Alonso A, Houlihan SL, Schwartz RE, Hissong E, Snopkowski C, Wrana JL, Ryan N, Butler LM, Church G, Swarbrick A, Mason CE, Martelotto LG.
Nat Biotechnol
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Nat Biotechnol
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The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs.
Authors: Authors: Park J, Gregorio R, Hissong E, Ozcelik E, Bartelo N, Dezem FS, Zhang L, Marção M, Chasteen H, Zheng Y, Abila E, Kim J, Nelson T, Proszynski J, Agyemang AA, Arikatla MR, Wani A, Liu Y, Metzger E, Rogers S, Divakar P, Dulai PS, Reeves J, Liang Y, Pan L, Bhattacharjee S, Patrick M, Young K, Heck A, Korukonda M, McGuire D, Wu L, Wardhani A, Beechem J, Church G, Lipkin SM, Berliner A, Patel S, Socciarelli F, Krumsiek J, Chandwani R, Monette S, Robinson B, Loda M, Elemento O, Martelotto L, Plummer J, Rendeiro AF, Alonso A, Schwartz RE, Houlihan SL, Mason CE.
bioRxiv
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bioRxiv
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Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells.
Authors: Authors: Madan E, Palma AM, Vudatha V, Kumar A, Bhoopathi P, Wilhelm J, Bernas T, Martin PC, Bilolikar G, Gogna A, Peixoto ML, Dreier I, Araujo TF, Garre E, Gustafsson A, Dorayappan KDP, Mamidi N, Sun Z, Yekelchyk M, Accardi D, Olsen AL, Lin L, Titelman AA, Bianchi M, Jessmon P, Farid EA, Pradhan AK, Neufeld L, Yeini E, Maji S, Pelham CJ, Kim H, Oh D, Rolfsnes HO, Marques RC, Lu A, Nagane M, Chaudhary S, Gupta K, Gogna KC, Bigio A, Bhoopathi K, Mannangatti P, Achary KG, Akhtar J, Belião S, Das S, Correia I, da Silva CL, Fialho AM, Poellmann MJ, Javius-Jones K, Hawkridge AM, Pal S, Shree KS, Rakha EA, Khurana S, Xiao G, Zhang D, Rijal A, Lyons C, Grossman SR, Turner DP, Pillappa R, Prakash K, Gupta G, Robinson GLWG, Koblinski J, Wang H, Singh G, Singh S, Rayamajhi S, Bacolod MD, Richards H, Sayeed S, Klein KP, Chelmow D, Satchi-Fainaro R, Selvendiran K, Connolly D, Thorsen FA, Bjerkvig R, Nephew KP, Idowu MO, Kühnel MP, Moskaluk C, Hong S, Redmond WL, Landberg G, Lopez-Beltran A, Poklepovic AS, Sanyal A, Fisher PB, Church GM, Menon U, Drapkin R, Godwin AK, Luo Y, Ackermann M, Tzankov A, Mertz KD, Jonigk D, Tsung A, Sidransky D, Trevino J, Saavedra AP, Winn R, Won KJ, Moreno E, Gogna R.
Nat Biotechnol
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Nat Biotechnol
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Large language models for drug discovery and development.
Authors: Authors: Zheng Y, Koh HY, Ju J, Yang M, May LT, Webb GI, Li L, Pan S, Church G.
Patterns (N Y)
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Patterns (N Y)
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Engineering gene drive docking sites in a haplolethal locus in Anopheles gambiae.
Authors: Authors: Smidler AL, Marrogi EA, Scott S, Mameli E, Abernathy D, Akbari OS, Church GM, Catteruccia F, Esvelt K.
Sci Rep
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Sci Rep
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Genetic signatures of exceptional longevity: a comprehensive analysis of coding region single nucleotide polymorphisms (SNPs) in centenarians and supercentenarians.
Authors: Authors: Raj APMS, Selvakumar G, Clement J, Church GM, Sivasubramaniam S.
Hum Genomics
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Hum Genomics
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Combinatorial protein barcodes enable self-correcting neuron tracing with nanoscale molecular context.
Authors: Authors: Park SY, Sheridan A, An B, Jarvis E, Lyudchik J, Patton W, Axup JY, Chan SW, Damstra HGJ, Leible D, Leung KS, Magno CA, Meeran A, Michalska JM, Rieger F, Wang C, Wu M, Church GM, Funke J, Huffman T, Leeper KGC, Truckenbrodt S, Winnubst J, Kornfeld JMR, Boyden ES, Rodriques SG, Payne AC.
bioRxiv
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bioRxiv
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