George Church headshot

George Church, Ph.D.

617-432-7562
Church Lab Website
On the ancestry and evolution of the extinct dire wolf.
Authors: Authors: Gedman GL, Pirovich KM, Oppenheimer J, Hyseni C, Cassatt-Johnstone M, Lucaci AG, Alexandre N, Troy W, Chao JC, Fedrigo O, Hoyt SJ, Grady PGS, Sacco S, Seligmann W, Dash A, Chokshi M, Knecht L, Papizan JB, Miyawaki T, Bocklandt S, Kelher J, Ord S, Gopalakrishnan S, Lin AT, Peecook BR, Perri A, Sinding MS, Larson G, Meachen J, Dalén L, vonHoldt B, Thomas P Gilbert M, Mason CE, O'Neill RJ, Karlsson EK, Cantarel BL, Martin GRR, Church G, Lamm B, Shapiro B.
Cell Genom
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Reply to: Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments.
Authors: Authors: Oliynyk RT, Church GM.
Nat Protoc
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Large-scale genome structure interrogation via recombinase-mediated rearrangements of multiplexed prime edits in repetitive elements.
Authors: Authors: Riedmayr LM, Koeppel J, Church GM, Parts L, Ferreira R.
Nat Protoc
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Elective genomic sequencing for adults in research, clinical and commercial contexts.
Authors: Authors: Linderman MD, Adelson SM, Berro TM, Anderson JL, Crawford SD, Cunningham TJ, Esplin ED, Ewing-Crawford AT, Nielsen DE, Pereira S, Schmidlen T, Andrighetti H, Bleyl SB, Church GM, Haverfield EV, Hegde M, Konstantinos LN, Kruszka P, Leonard D, May T, McGinniss M, Pandya V, Schadt EE, Greshake Tzovaras B, Zettler B, McGuire AL, Green RC.
BMC Med Genomics
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Derivation of elephant induced pluripotent stem cells.
Authors: Authors: Appleton E, Korover N, Hong K, Ambriz-Peña X, Tanaka Y, Ashkenazy-Titelman A, Rasmussen-Ivey C, Rodríguez-Caycedo C, Bhide K, Bai H, Queiroz A, Nelson JW, Rathod G, Morgan M, Mastracci A, Nelson TM, Knox G, McNutt B, Malviya N, Zhang K, Kowalczyk A, Bow A, McLendon B, Slamecka J, Ryon K, Proszynski J, Houerbi N, Kleinman AS, Poon CL, Kiso W, James M, Park IH, Gray C, Pearson VR, Mason CE, Cantarel BL, Koehler KR, Shapiro B, Kehler J, Lamm B, Church G, Hysolli E.
Nat Methods
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Probing the limits of genetic recoding using multi-omics-guided evolution.
Authors: Authors: Nyerges A, Chiappino-Pepe A, Budnik B, Baas-Thomas M, Rhuby E, Flynn R, Yan S, Ostrov N, Liu M, Wang M, Zheng Q, Hu F, Chen K, Rudolph A, Chen D, Ahn J, Spencer O, Ayalavarapu V, Tarver A, Harmon-Smith M, Hamilton M, Blaby I, Yoshikuni Y, Hajian B, Jin A, Kintses B, Szamel M, Seregi V, Shen Y, Li Z, Church GM.
Nat Commun
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Programmable Nucleic Acid Sensing in Human Cells Using Circularizable ssDNA.
Authors: Authors: Mahas A, Ferreira R, Riedmayr LM, Church GM.
Nat Commun
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Architectural fragility of gene regulatory networks underlies hematopoietic stem cell aging.
Authors: Authors: Stevens HP, Yücel AD, Gould RA, Cai G, Gladyshev VN, Plesa AM, Church GM.
bioRxiv
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DNA Cut-Ligation Cyclization Surpasses Jacobson-Stockmayer J-Factor Expectations by over Threefold.
Authors: Authors: Oliynyk RT, Church GM.
Biomolecules
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A platform to design and optimise fluorogenic scFvs for detection of interleukin 33.
Authors: Authors: Reese AE, Karmakar U, Restori M, Hermoso MA, Church GM, Kuru E, Vendrell M.
Chem Sci
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