Engineering posttranslational proofreading to discriminate nonstandard amino acids.
Authors: Authors: Kunjapur AM, Stork DA, Kuru E, Vargas-Rodriguez O, Landon M, Söll D, Church GM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Beyond editing to writing large genomes.
Cogenerating Synthetic Parts toward a Self-Replicating System.
Authors: Authors: Li J, Haas W, Jackson K, Kuru E, Jewett MC, Fan ZH, Gygi S, Church GM.
ACS Synth Biol
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ACS Synth Biol
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CRISPR-Cas encoding of a digital movie into the genomes of a population of living bacteria.
Optimizing complex phenotypes through model-guided multiplex genome engineering.
Authors: Authors: Kuznetsov G, Goodman DB, Filsinger GT, Landon M, Rohland N, Aach J, Lajoie MJ, Church GM.
Genome Biol
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Genome Biol
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Millstone: software for multiplex microbial genome analysis and engineering.
Authors: Authors: Goodman DB, Kuznetsov G, Lajoie MJ, Ahern BW, Napolitano MG, Chen KY, Chen C, Church GM.
Genome Biol
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Genome Biol
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sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity.
An unbiased index to quantify participant's phenotypic contribution to an open-access cohort.
Authors: Authors: Chan Y, Tung M, Garruss AS, Zaranek SW, Chan YK, Lunshof JE, Zaranek AW, Ball MP, Chou MF, Lim ET, Church GM.
Sci Rep
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Sci Rep
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Addressing the ethical issues raised by synthetic human entities with embryo-like features.
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.
Authors: Authors: Rock JM, Hopkins FF, Chavez A, Diallo M, Chase MR, Gerrick ER, Pritchard JR, Church GM, Rubin EJ, Sassetti CM, Schnappinger D, Fortune SM.
Nat Microbiol
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Nat Microbiol
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