George Church headshot

George Church, Ph.D.

617-432-7562
Church Lab Website
Large language models for drug discovery and development.
Authors: Authors: Zheng Y, Koh HY, Ju J, Yang M, May LT, Webb GI, Li L, Pan S, Church G.
Patterns (N Y)
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Engineering gene drive docking sites in a haplolethal locus in Anopheles gambiae.
Authors: Authors: Smidler AL, Marrogi EA, Scott S, Mameli E, Abernathy D, Akbari OS, Church GM, Catteruccia F, Esvelt K.
Sci Rep
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Genetic signatures of exceptional longevity: a comprehensive analysis of coding region single nucleotide polymorphisms (SNPs) in centenarians and supercentenarians.
Authors: Authors: Raj APMS, Selvakumar G, Clement J, Church GM, Sivasubramaniam S.
Hum Genomics
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Combinatorial protein barcodes enable self-correcting neuron tracing with nanoscale molecular context.
Authors: Authors: Park SY, Sheridan A, An B, Jarvis E, Lyudchik J, Patton W, Axup JY, Chan SW, Damstra HGJ, Leible D, Leung KS, Magno CA, Meeran A, Michalska JM, Rieger F, Wang C, Wu M, Church GM, Funke J, Huffman T, Leeper KGC, Truckenbrodt S, Winnubst J, Kornfeld JMR, Boyden ES, Rodriques SG, Payne AC.
bioRxiv
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Validation of human sensory neurons derived from inducible pluripotent stem cells as a model for latent infection and reactivation by herpes simplex virus 1.
Authors: Authors: Oh HS, Chou S-F, Raja P, Shim J, Das B, Pesola JM, Romero N, Lee JS, Ng A, Buttermore ED, Church G, Woolf CJ, Coen DM, Knipe DM.
mBio
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Author Correction: PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins.
Authors: Authors: Zhang C, Hou J, Li Z, Shen Q, Bai H, Chen L, Shen J, Wang P, Su Y, Li J, Zhang Q, Liu C, Xi X, Qi F, Chen Y, Xie X, Ye AY, Liu X, Plebani R, Church G, Si L.
Nat Chem Biol
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PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins.
Authors: Authors: Zhang C, Hou J, Li Z, Shen Q, Bai H, Chen L, Shen J, Wang P, Su Y, Li J, Zhang Q, Liu C, Xi X, Qi F, Chen Y, Xie X, Ye AY, Liu X, Plebani R, Church G, Si L.
Nat Chem Biol
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Initiation of meiosis from human iPSCs under defined conditions through identification of regulatory factors.
Authors: Authors: Smela MP, Adams J, Ma C, Breimann L, Widocki U, Dobre B, Shioda T, Church GM.
Sci Adv
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Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues.
Authors: Authors: Stein J, Ericsson M, Nofal M, Magni L, Aufmkolk S, McMillan RB, Breimann L, Herlihy CP, Lee SD, Willemin A, Wohlmann J, Arguedas-Jimenez L, Yin P, Pombo A, Church GM, Wu CT.
Proc Natl Acad Sci U S A
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Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research.
Authors: Authors: Zwi-Dantsis L, Jayarajan V, Church GM, Kamm RD, de Magalhães JP, Moeendarbary E.
Adv Healthc Mater
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