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George Church, Ph.D.

617-432-7562
Church Lab Website
Cell therapy strategies for COVID-19: Current approaches and potential applications.
Authors: Authors: Zaki MM, Lesha E, Said K, Kiaee K, Robinson-McCarthy L, George H, Hanna A, Appleton E, Liu S, Ng AHM, Khoshakhlagh P, Church GM.
Sci Adv
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Publisher Correction: Voices of biotech leaders.
Authors: Authors: Bosley K, Casebourn C, Chan P, Chen J, Chen M, Church G, Cumbers J, de Wouters T, Dewey-Hagborg H, Duportet X, Ene-Obong A, Elizondo A, Farrar J, Gates B, Gatto F, Giwa S, Godec J, Gold S, LeProust E, Lunshof J, Martucci E, Heath MM, Mellad J, Oudova V, Oxman N, Regev A, Richardson S, Scott CT, Sherkow J, Sibener L, Tarragó T, Terry S, Venter JC, Wang S, Wickramasekara S, Yadi H, Yang L, Zhao B.
Nat Biotechnol
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Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier.
Authors: Authors: Yonker LM, Gilboa T, Ogata AF, Senussi Y, Lazarovits R, Boribong BP, Bartsch YC, Loiselle M, Rivas MN, Porritt RA, Lima R, Davis JP, Farkas EJ, Burns MD, Young N, Mahajan VS, Hajizadeh S, Lopez XIH, Kreuzer J, Morris R, Martinez EE, Han I, Griswold K, Barry NC, Thompson DB, Church G, Edlow AG, Haas W, Pillai S, Arditi M, Alter G, Walt DR, Fasano A.
J Clin Invest
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Deep representation learning improves prediction of LacI-mediated transcriptional repression.
Authors: Authors: Garruss AS, Collins KM, Church GM.
Proc Natl Acad Sci U S A
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Synthetic auxotrophy remains stable after continuous evolution and in coculture with mammalian cells.
Authors: Authors: Kunjapur AM, Napolitano MG, Hysolli E, Noguera K, Appleton EM, Schubert MG, Jones MA, Iyer S, Mandell DJ, Church GM.
Sci Adv
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Barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel in situ analyses.
Authors: Authors: Liu S, Punthambaker S, Iyer EPR, Ferrante T, Goodwin D, Fürth D, Pawlowski AC, Jindal K, Tam JM, Mifflin L, Alon S, Sinha A, Wassie AT, Chen F, Cheng A, Willocq V, Meyer K, Ling KH, Camplisson CK, Kohman RE, Aach J, Lee JH, Yankner BA, Boyden ES, Church GM.
Nucleic Acids Res
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L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma.
Authors: Authors: Norman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Nat Methods
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Voices of biotech leaders.
Authors: Authors: Bosley K, Casebourn C, Chan P, Chen J, Chen M, Church G, Cumbers J, de Wouters T, Dewey-Hagborg H, Duportet X, Ene-Obong A, Elizondo A, Farrar J, Gates B, Gatto F, Giwa S, Godec J, Gold S, LeProust E, Lunshof J, Martucci E, Heath MM, Mellad J, Oudova V, Oxman N, Regev A, Richardson S, Scott CT, Sherkow J, Sibener L, Tarragó T, Terry S, Venter JC, Wang S, Wickramasekara S, Yadi H, Yang L, Zhao B.
Nat Biotechnol
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Deep diversification of an AAV capsid protein by machine learning.
Authors: Authors: Bryant DH, Bashir A, Sinai S, Jain NK, Ogden PJ, Riley PF, Church GM, Colwell LJ, Kelsic ED.
Nat Biotechnol
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Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning.
Authors: Authors: Xiang X, Corsi GI, Anthon C, Qu K, Pan X, Liang X, Han P, Dong Z, Liu L, Zhong J, Ma T, Wang J, Zhang X, Jiang H, Xu F, Liu X, Xu X, Wang J, Yang H, Bolund L, Church GM, Lin L, Gorodkin J, Luo Y.
Nat Commun
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