George Church

George Church, Ph.D.

617-432-7562

Church Lab Website

Publications

High-throughput functional variant screens via in vivo production of single-stranded DNA.

Authors: Authors: Schubert MG, Goodman DB, Wannier TM, Kaur D, Farzadfard F, Lu TK, Shipman SL, Church GM.
Proc Natl Acad Sci U S A 2021-05-04
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Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency.

Authors: Authors: Sun B, Yang X, Hou F, Yu X, Wang Q, Oh HS, Raja P, Pesola JM, Vanni EAH, McCarron S, Morris-Love J, Ng AHM, Church GM, Knipe DM, Coen DM, Pan D.
Nat Microbiol 2021-05-01
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Ultrasensitive Measurement of Both SARS-CoV-2 RNA and Antibodies from Saliva.

Authors: Authors: Ter-Ovanesyan D, Gilboa T, Lazarovits R, Rosenthal A, Yu X, Li JZ, Church GM, Walt DR.
Anal Chem 2021-04-06
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Low-N protein engineering with data-efficient deep learning.

Authors: Authors: Biswas S, Khimulya G, Alley EC, Esvelt KM, Church GM.
Nat Methods 2021-04-01
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Characterizing the portability of phage-encoded homologous recombination proteins.

Authors: Authors: Filsinger GT, Wannier TM, Pedersen FB, Lutz ID, Zhang J, Stork DA, Debnath A, Gozzi K, Kuchwara H, Volf V, Wang S, Rios X, Gregg CJ, Lajoie MJ, Shipman SL, Aach J, Laub MT, Church GM.
Nat Chem Biol 2021-04-01
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Lineage barcoding in mice with homing CRISPR.

Authors: Authors: Leeper K, Kalhor K, Vernet A, Graveline A, Church GM, Mali P, Kalhor R.
Nat Protoc 2021-04-01
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A comprehensive library of human transcription factors for cell fate engineering.

Authors: Authors: Ng AHM, Khoshakhlagh P, Rojo Arias JE, Pasquini G, Wang K, Swiersy A, Shipman SL, Appleton E, Kiaee K, Kohman RE, Vernet A, Dysart M, Leeper K, Saylor W, Huang JY, Graveline A, Taipale J, Hill DE, Vidal M, Melero-Martin JM, Busskamp V, Church GM.
Nat Biotechnol 2021-04-01
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A computer-guided design tool to increase the efficiency of cellular conversions.

Authors: Authors: Jung S, Appleton E, Ali M, Church GM, Del Sol A.
Nat Commun 2021-03-12
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Citizen-centered, auditable and privacy-preserving population genomics.

Authors: Authors: Grishin D, Raisaro JL, Troncoso-Pastoriza JR, Obbad K, Quinn K, Misbach M, Gollhardt J, Sa J, Fellay J, Church GM, Hubaux JP.
Nat Comput Sci 2021-03-01
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Chromosome-scale, haplotype-resolved assembly of human genomes.

Authors: Authors: Garg S, Fungtammasan A, Carroll A, Chou M, Schmitt A, Zhou X, Mac S, Peluso P, Hatas E, Ghurye J, Maguire J, Mahmoud M, Cheng H, Heller D, Zook JM, Moemke T, Marschall T, Sedlazeck FJ, Aach J, Chin CS, Church GM, Li H.
Nat Biotechnol 2021-03-01
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