George Church

George Church, Ph.D.

617-432-7562

Church Lab Website

Publications

In situ genome sequencing resolves DNA sequence and structure in intact biological samples.

Authors: Authors: Payne AC, Chiang ZD, Reginato PL, Mangiameli SM, Murray EM, Yao CC, Markoulaki S, Earl AS, Labade AS, Jaenisch R, Church GM, Boyden ES, Buenrostro JD, Chen F.
Science 2021-02-26
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Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses.

Authors: Authors: Chan YK, Wang SK, Chu CJ, Copland DA, Letizia AJ, Costa Verdera H, Chiang JJ, Sethi M, Wang MK, Neidermyer WJ, Chan Y, Lim ET, Graveline AR, Sanchez M, Boyd RF, Vihtelic TS, Inciong RGCO, Slain JM, Alphonse PJ, Xue Y, Robinson-McCarthy LR, Tam JM, Jabbar MH, Sahu B, Adeniran JF, Muhuri M, Tai PWL, Xie J, Krause TB, Vernet A, Pezone M, Xiao R, Liu T, Wang W, Kaplan HJ, Gao G, Dick AD, Mingozzi F, McCall MA, Cepko CL, Church GM.
Sci Transl Med 2021-02-10
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Extensive germline genome engineering in pigs.

Authors: Authors: Yue Y, Xu W, Kan Y, Zhao HY, Zhou Y, Song X, Wu J, Xiong J, Goswami D, Yang M, Lamriben L, Xu M, Zhang Q, Luo Y, Guo J, Mao S, Jiao D, Nguyen TD, Li Z, Layer JV, Li M, Paragas V, Youd ME, Sun Z, Ding Y, Wang W, Dou H, Song L, Wang X, Le L, Fang X, George H, Anand R, Wang SY, Westlin WF, Güell M, Markmann J, Qin W, Gao Y, Wei HJ, Church GM, Yang L.
Nat Biomed Eng 2021-02-01
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Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems.

Authors: Authors: Alon S, Goodwin DR, Sinha A, Wassie AT, Chen F, Daugharthy ER, Bando Y, Kajita A, Xue AG, Marrett K, Prior R, Cui Y, Payne AC, Yao CC, Suk HJ, Wang R, Yu CJ, Tillberg P, Reginato P, Pak N, Liu S, Punthambaker S, Iyer EPR, Kohman RE, Miller JA, Lein ES, Lako A, Cullen N, Rodig S, Helvie K, Abravanel DL, Wagle N, Johnson BE, Klughammer J, Slyper M, Waldman J, Jané-Valbuena J, Rozenblatt-Rosen O, Regev A, Church GM, Marblestone AH, Boyden ES.
Science 2021-01-29
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Multiplex Single-Molecule Kinetics of Nanopore-Coupled Polymerases.

Authors: Authors: Palla M, Punthambaker S, Stranges B, Vigneault F, Nivala J, Wiegand D, Ayer A, Craig T, Gremyachinskiy D, Franklin H, Sun S, Pollard J, Trans A, Arnold C, Schwab C, Mcgaw C, Sarvabhowman P, Dalal D, Thai E, Amato E, Lederman I, Taing M, Kelley S, Qwan A, Fuller CW, Roever S, Church GM.
ACS Nano 2021-01-26
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Algorithms for the selection of fluorescent reporters.

Authors: Authors: Vaidyanathan P, Appleton E, Tran D, Vahid A, Church G, Densmore D.
Commun Biol 2021-01-26
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Anomalous COVID-19 tests hinder researchers.

Authors: Authors: Robinson-McCarthy LR, Mijalis AJ, Filsinger GT, de Puig H, Donghia NM, Schaus TE, Rasmussen RA, Ferreira R, Lunshof JE, Chao G, Ter-Ovanesyan D, Dodd O, Kuru E, Sesay AM, Rainbow J, Pawlowski AC, Wannier TM, Yin P, Collins JJ, Ingber DE, Church GM, Tam JM.
Science 2021-01-15
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TBDB: a database of structurally annotated T-box riboswitch:tRNA pairs.

Authors: Authors: Marchand JA, Pierson Smela MD, Jordan THH, Narasimhan K, Church GM.
Nucleic Acids Res 2021-01-08
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Porcine genome engineering for xenotransplantation.

Authors: Authors: Niu D, Ma X, Yuan T, Niu Y, Xu Y, Sun Z, Ping Y, Li W, Zhang J, Wang T, Church GM.
Adv Drug Deliv Rev 2021-01-01
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Recombineering and MAGE.

Authors: Authors: Wannier TM, Ciaccia PN, Ellington AD, Filsinger GT, Isaacs FJ, Javanmardi K, Jones MA, Kunjapur AM, Nyerges A, Pal C, Schubert MG, Church GM.
Nat Rev Methods Primers 2021-01-01
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