George Church headshot

George Church, Ph.D.

617-432-7562
Church Lab Website
Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures.
Authors: Authors: Eroshenko N, Gill T, Keaveney MK, Church GM, Trevejo JM, Rajaniemi H.
Nat Biotechnol
View full abstract on Pubmed
Improved bacterial recombineering by parallelized protein discovery.
Authors: Authors: Wannier TM, Nyerges A, Kuchwara HM, Czikkely M, Balogh D, Filsinger GT, Borders NC, Gregg CJ, Lajoie MJ, Rios X, Pál C, Church GM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Enabling large-scale genome editing at repetitive elements by reducing DNA nicking.
Authors: Authors: Smith CJ, Castanon O, Said K, Volf V, Khoshakhlagh P, Hornick A, Ferreira R, Wu CT, Güell M, Garg S, Ng AHM, Myllykallio H, Church GM.
Nucleic Acids Res
View full abstract on Pubmed
Korean Genome Project: 1094 Korean personal genomes with clinical information.
Authors: Authors: Jeon S, Bhak Y, Choi Y, Jeon Y, Kim S, Jang J, Jang J, Blazyte A, Kim C, Kim Y, Shim J, Kim N, Kim YJ, Park SG, Kim J, Cho YS, Park Y, Kim HM, Kim BC, Park NH, Shin ES, Kim BC, Bolser D, Manica A, Edwards JS, Church G, Lee S, Bhak J.
Sci Adv
View full abstract on Pubmed
A haplotype-aware de novo assembly of related individuals using pedigree sequence graph.
Authors: Authors: Garg S, Aach J, Li H, Sebenius I, Durbin R, Church G.
Bioinformatics
View full abstract on Pubmed
aKLOTHO and sTGFßR2 treatment counteract the osteoarthritic phenotype developed in a rat model.
Authors: Authors: Martinez-Redondo P, Guillen-Guillen I, Davidsohn N, Wang C, Prieto J, Kurita M, Hatanaka F, Zhong C, Hernandez-Benitez R, Hishida T, Lezaki T, Sakamoto A, Nemeth AN, Hishida Y, Esteban CR, Shojima K, Huang L, Shokhirev M, Nuñez-Delicado E, Campistol JM, Guillen-Vicente I, Rodriguez-Iñigo E, Lopez-Alcorocho JM, Guillen-Vicente M, Church G, Reddy P, Guillen-Garcia P, Liu GH, Belmonte JCI.
Protein Cell
View full abstract on Pubmed
A Deep Learning Approach to Antibiotic Discovery.
Authors: Authors: Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ.
Cell
View full abstract on Pubmed
Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer.
Authors: Authors: Zhang H, Schaefer A, Wang Y, Hodge RG, Blake DR, Diehl JN, Papageorge AG, Stachler MD, Liao J, Zhou J, Wu Z, Akarca FG, de Klerk LK, Derks S, Pierobon M, Hoadley KA, Wang TC, Church G, Wong KK, Petricoin EF, Cox AD, Lowy DR, Der CJ, Bass AJ.
Cancer Discov
View full abstract on Pubmed
Benchmarking evolutionary tinkering underlying human-viral molecular mimicry shows multiple host pulmonary-arterial peptides mimicked by SARS-CoV-2.
Authors: Authors: Venkatakrishnan AJ, Kayal N, Anand P, Badley AD, Church GM, Soundararajan V.
Cell Death Discov
View full abstract on Pubmed
The Role of Synthetic Biology in Atmospheric Greenhouse Gas Reduction: Prospects and Challenges.
Authors: Authors: DeLisi C, Patrinos A, MacCracken M, Drell D, Annas G, Arkin A, Church G, Cook-Deegan R, Jacoby H, Lidstrom M, Melillo J, Milo R, Paustian K, Reilly J, Roberts RJ, Segrè D, Solomon S, Woolf D, Wullschleger SD, Yang X.
Biodes Res
View full abstract on Pubmed