Predispositional genome sequencing in healthy adults: design, participant characteristics, and early outcomes of the PeopleSeq Consortium.
Authors: Authors: Zoltick ES, Linderman MD, McGinniss MA, Ramos E, Ball MP, Church GM, Leonard DGB, Pereira S, McGuire AL, Caskey CT, Sanderson SC, Schadt EE, Nielsen DE, Crawford SD, Green RC.
Genome Med
View full abstract on Pubmed
Genome Med
View full abstract on Pubmed
REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease.
Authors: Authors: Meyer K, Feldman HM, Lu T, Drake D, Lim ET, Ling KH, Bishop NA, Pan Y, Seo J, Lin YT, Su SC, Church GM, Tsai LH, Yankner BA.
Cell Rep
View full abstract on Pubmed
Cell Rep
View full abstract on Pubmed
CRISPR-C: circularization of genes and chromosome by CRISPR in human cells.
Authors: Authors: Møller HD, Lin L, Xiang X, Petersen TS, Huang J, Yang L, Kjeldsen E, Jensen UB, Zhang X, Liu X, Xu X, Wang J, Yang H, Church GM, Bolund L, Regenberg B, Luo Y.
Nucleic Acids Res
View full abstract on Pubmed
Nucleic Acids Res
View full abstract on Pubmed
Opinion: Advocating for science progress as a human right.
Authors: Authors: Porsdam Mann S, Donders Y, Mitchell C, Bradley VJ, Chou MF, Mann M, Church G, Porsdam H.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow.
Authors: Authors: Brunk E, Chang RL, Xia J, Hefzi H, Yurkovich JT, Kim D, Buckmiller E, Wang HH, Cho BK, Yang C, Palsson BO, Church GM, Lewis NE.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Establishing a Cell-Free Vibrio natriegens Expression System.
Authors: Authors: Wiegand DJ, Lee HH, Ostrov N, Church GM.
ACS Synth Biol
View full abstract on Pubmed
ACS Synth Biol
View full abstract on Pubmed
CRISPR Guide RNA Cloning for Mammalian Systems.
Authors: Authors: Nageshwaran S, Chavez A, Cher Yeo N, Guo X, Lance-Byrne A, Tung A, Collins JJ, Church GM.
J Vis Exp
View full abstract on Pubmed
J Vis Exp
View full abstract on Pubmed
Developmental barcoding of whole mouse via homing CRISPR.
Authors: Authors: Kalhor R, Kalhor K, Mejia L, Leeper K, Graveline A, Mali P, Church GM.
Science
View full abstract on Pubmed
Science
View full abstract on Pubmed
Biosensor libraries harness large classes of binding domains for construction of allosteric transcriptional regulators.
Authors: Authors: Juárez JF, Lecube-Azpeitia B, Brown SL, Johnston CD, Church GM.
Nat Commun
View full abstract on Pubmed
Nat Commun
View full abstract on Pubmed
Building Capacity for a Global Genome Editing Observatory: Institutional Design.
Authors: Authors: Saha K, Hurlbut JB, Jasanoff S, Ahmed A, Appiah A, Bartholet E, Baylis F, Bennett G, Church G, Cohen IG, Daley G, Finneran K, Hurlbut W, Jaenisch R, Lwoff L, Kimes JP, Mills P, Moses J, Park BS, Parens E, Salzman R, Saxena A, Simmet H, Simoncelli T, Snead OC, Rajan KS, Truog RD, Williams P, Woopen C.
Trends Biotechnol
View full abstract on Pubmed
Trends Biotechnol
View full abstract on Pubmed