George Church

George Church, Ph.D.

617-432-7562

Church Lab Website

Publications

Comparative Transcriptome Analysis of Acne vulgaris, Rosacea, and Hidradenitis Suppurativa Supports High Dose Dietary Zinc as a Therapeutic Agent.

Authors: Authors: Li L, Hajam I, McGee JS, Tang Z, Zhang Y, Badey N, Mintzer E, Zhang Z, Liu GY, Church GM, Wang Y.
medRxiv 2023-12-04
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Engineering Ca2+-Dependent DNA Polymerase Activity.

Authors: Authors: Biggs BW, de Paz AM, Bhan NJ, Cybulski TR, Church GM, Tyo KEJ.
ACS Synth Biol 2023-11-17
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SeqVerify: An accessible analysis tool for cell line genomic integrity, contamination, and gene editing outcomes.

Authors: Authors: Smela MP, Pepe V, Church GM.
bioRxiv 2023-10-28
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Strategies to identify and edit improvements in synthetic genome segments episomally.

Authors: Authors: Rudolph A, Nyerges A, Chiappino-Pepe A, Landon M, Baas-Thomas M, Church G.
Nucleic Acids Res 2023-10-13
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Viral activation and ecological restructuring characterize a microbiome axis of spaceflight-associated immune activation.

Authors: Authors: Tierney BT, Kim J, Overbey EG, Ryon KA, Foox J, Sierra M, Bhattacharya C, Damle N, Najjar D, Park J, Garcia Medina S, Houerbi N, Meydan C, Wain Hershberg J, Qiu J, Kleinman A, Al Ghalith G, MacKay M, Afshin EE, Dhir R, Borg J, Gatt C, Brereton N, Readhead B, Beyaz S, Venkateswaran KJ, Blease K, Moreno J, Boddicker A, Zhao J, Lajoie B, Scott RT, Altomare A, Kruglyak S, Levy S, Church G, Mason CE.
Res Sq 2023-10-10
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PAM-flexible genome editing with an engineered chimeric Cas9.

Authors: Authors: Zhao L, Koseki SRT, Silverstein RA, Amrani N, Peng C, Kramme C, Savic N, Pacesa M, Rodríguez TC, Stan T, Tysinger E, Hong L, Yudistyra V, Ponnapati MR, Jacobson JM, Church GM, Jakimo N, Truant R, Jinek M, Kleinstiver BP, Sontheimer EJ, Chatterjee P.
Nat Commun 2023-10-04
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Design and testing of a humanized porcine donor for xenotransplantation.

Authors: Authors: Anand RP, Layer JV, Heja D, Hirose T, Lassiter G, Firl DJ, Paragas VB, Akkad A, Chhangawala S, Colvin RB, Ernst RJ, Esch N, Getchell K, Griffin AK, Guo X, Hall KC, Hamilton P, Kalekar LA, Kan Y, Karadagi A, Li F, Low SC, Matheson R, Nehring C, Otsuka R, Pandelakis M, Policastro RA, Pols R, Queiroz L, Rosales IA, Serkin WT, Stiede K, Tomosugi T, Xue Y, Zentner GE, Angeles-Albores D, Chris Chao J, Crabtree JN, Harken S, Hinkle N, Lemos T, Li M, Pantano L, Stevens D, Subedar OD, Tan X, Yin S, Anwar IJ, Aufhauser D, Capuano S, Kaufman DB, Knechtle SJ, Kwun J, Shanmuganayagam D, Markmann JF, Church GM, Curtis M, Kawai T, Youd ME, Qin W.
Nature 2023-10-01
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Reliable multiplex generation of pooled induced pluripotent stem cells.

Authors: Authors: Smullen M, Olson MN, Reichert JM, Dawes P, Murray LF, Baer CE, Wang Q, Readhead B, Church GM, Lim ET, Chan Y.
Cell Rep Methods 2023-09-25
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Antenna Modification in a Fast-Growing Cyanobacterium Synechococcus elongatus UTEX 2973 Leads to Improved Efficiency and Carbon-Neutral Productivity.

Authors: Authors: Sengupta A, Bandyopadhyay A, Schubert MG, Church GM, Pakrasi HB.
Microbiol Spectr 2023-08-17
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Transcriptomic reprogramming for neuronal age reversal.

Authors: Authors: Plesa AM, Shadpour M, Boyden E, Church GM.
Hum Genet 2023-08-01
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