George Church headshot

George Church, Ph.D.

617-432-7562
Church Lab Website
Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells.
Authors: Authors: Yang L, Grishin D, Wang G, Aach J, Zhang CZ, Chari R, Homsy J, Cai X, Zhao Y, Fan JB, Seidman C, Seidman J, Pu W, Church G.
Nat Commun
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Rapid neurogenesis through transcriptional activation in human stem cells.
Authors: Authors: Busskamp V, Lewis NE, Guye P, Ng AH, Shipman SL, Byrne SM, Sanjana NE, Murn J, Li Y, Li S, Stadler M, Weiss R, Church GM.
Mol Syst Biol
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Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA).
Authors: Authors: Güell M, Yang L, Church GM.
Bioinformatics
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A bacterial strain with a unique quadruplet codon specifying non-native amino acids.
Authors: Authors: Chatterjee A, Lajoie MJ, Xiao H, Church GM, Schultz PG.
Chembiochem
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Biotechnology. Regulating gene drives.
Authors: Authors: Oye KA, Esvelt K, Appleton E, Catteruccia F, Church G, Kuiken T, Lightfoot SB, McNamara J, Smidler A, Collins JP.
Science
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B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes.
Authors: Authors: Stern JN, Yaari G, Vander Heiden JA, Church G, Donahue WF, Hintzen RQ, Huttner AJ, Laman JD, Nagra RM, Nylander A, Pitt D, Ramanan S, Siddiqui BA, Vigneault F, Kleinstein SH, Hafler DA, O'Connor KC.
Sci Transl Med
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Concerning RNA-guided gene drives for the alteration of wild populations.
Authors: Authors: Esvelt KM, Smidler AL, Catteruccia F, Church GM.
Elife
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CRISPR/Cas9-Directed Genome Editing of Cultured Cells.
Authors: Authors: Yang L, Yang JL, Byrne S, Pan J, Church GM.
Curr Protoc Mol Biol
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CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing.
Authors: Authors: Montague TG, Cruz JM, Gagnon JA, Church GM, Valen E.
Nucleic Acids Res
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Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies.
Authors: Authors: Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zhang D, Zangi L, Geva J, Roberts AE, Ma Q, Ding J, Chen J, Wang DZ, Li K, Wang J, Wanders RJ, Kulik W, Vaz FM, Laflamme MA, Murry CE, Chien KR, Kelley RI, Church GM, Parker KK, Pu WT.
Nat Med
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