Jeannie Lee headshot

Jeannie T. Lee, M.D., Ph.D.

Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
617-726-5943
Lee Lab Website
Detection of nascent RNA, single-copy DNA and protein localization by immunoFISH in mouse germ cells and preimplantation embryos.
Authors: Authors: Namekawa SH, Lee JT.
Nat Protoc
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Genome-wide identification of polycomb-associated RNAs by RIP-seq.
Authors: Authors: Zhao J, Ohsumi TK, Kung JT, Ogawa Y, Grau DJ, Sarma K, Song JJ, Kingston RE, Borowsky M, Lee JT.
Mol Cell
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Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome.
Authors: Authors: Sarma K, Levasseur P, Aristarkhov A, Lee JT.
Proc Natl Acad Sci U S A
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Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects.
Authors: Authors: Nordstrand LM, Svärd J, Larsen E, Nilsen A, Ougland R, Furu K, Lien GF, Rognes T, Namekawa SH, Lee JT, Klungland A.
PLoS One
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The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation.
Authors: Authors: Tian D, Sun S, Lee JT.
Cell
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The X as model for RNA's niche in epigenomic regulation.
Authors: Authors: Lee JT.
Cold Spring Harb Perspect Biol
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Retinoic acid accelerates downregulation of the Xist repressor, Oct4, and increases the likelihood of Xist activation when Tsix is deficient.
Authors: Authors: Ahn JY, Lee JT.
BMC Dev Biol
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Two-step imprinted X inactivation: repeat versus genic silencing in the mouse.
Authors: Authors: Namekawa SH, Payer B, Huynh KD, Jaenisch R, Lee JT.
Mol Cell Biol
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Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.
Authors: Authors: Lengner CJ, Gimelbrant AA, Erwin JA, Cheng AW, Guenther MG, Welstead GG, Alagappan R, Frampton GM, Xu P, Muffat J, Santagata S, Powers D, Barrett CB, Young RA, Lee JT, Jaenisch R, Mitalipova M.
Cell
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Extending the frontiers of epigenetic regulation.
Authors: Authors: Paro R, Lee JT.
Curr Opin Genet Dev
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